Background Patients with critical illness can lose more than 15% of muscle mass in one
week, and this can have long-term detrimental effects. However, there is currently no …

A substantial number of patients admitted to the ICU because of an acute illness,
complicated surgery, severe trauma, or burn injury will develop a de novo form of muscle …

Objective: Survivors of severe critical illness frequently develop substantial and persistent
physical complications, including muscle weakness, impaired physical function, and …

Survivorship after critical illness is an increasingly important health-care concern as ICU use
continues to increase while ICU mortality is decreasing. Survivors of critical illness …

Purpose This study aimed to (1) document patterns of quadriceps muscle wasting in the first
10 days of admission and (2) determine the relationship between muscle ultrasonography …

Rationale: Intensive care unit (ICU)-acquired weakness is a frequent complication of critical
illness. It is unclear whether it is a marker or mediator of poor outcomes. Objectives: To …

Rationale: Profound muscle weakness during and after critical illness is termed intensive
care unit–acquired weakness (ICUAW). Objectives: To develop diagnostic …

Background Muscular weakness and/or muscle wasting is recognized as a key medical
problem in critically ill patients on intensive care units (ICUs) worldwide. Methods and …

Critical illness polyneuropathies (CIP) and myopathies (CIM) are common complications of
critical illness. Several weakness syndromes are summarized under the term intensive care …

Rationale: Early physical therapy (PT) interventions may benefit patients with acute
respiratory failure by preventing or attenuating neuromuscular weakness. However, the …