Besides its role as an energy storage organ, adipose tissue can be viewed as a dynamic
and complex endocrine organ, which produces and secretes several adipokines, including …

Loss of skeletal muscle mass and strength has recently become a hot research topic with the
extension of life span and an increasingly sedentary lifestyle in modern society …

Exercise and dietary intervention are currently available strategies to treat nonalcoholic fatty
liver disease (NAFLD), while the underlying mechanism remains controversial. Emerging …

Macroautophagy (herein referred to as autophagy) is an evolutionarily conserved
mechanism of adaptation to adverse microenvironmental conditions, including limited …

Endurance exercise-mediated multisystemic adaptations are known to mitigate metabolism-
related disorders such as obesity and type 2 diabetes mellitus (T2DM). However, the …

Exercise reduces the risk of a multitude of disorders, from metabolic disease to cancer, but
the molecular mechanisms mediating the protective effects of exercise are not completely …

Erythroferrone (ERFE) is the main erythroid regulator of hepcidin, the homeostatic hormone
controlling plasma iron levels and total body iron. When the release of erythropoietin from …

To maintain and restore skeletal muscle mass and function is essential for healthy aging. We
have found that myonectin acts as a cardioprotective myokine. Here, we investigate the …

Myokines are muscle‐derived cytokines and chemokines that act extensively on organs and
exert beneficial metabolic functions in the whole‐body through specific signal networks …

The skeletal muscle is the largest organ in the body, by mass. It is also the regulator of
glucose homeostasis, responsible for 80% of postprandial glucose uptake from the …