The membrane proteins CD38 and CD157 belong to an evolutionarily conserved family of
enzymes that play crucial roles in human physiology. Expressed in distinct patterns in most …

Human CD38 is the mammalian prototype of a family of proteins which share structural
similarities and an ectoenzymatic activity involved in the production of calcium mobilizing …

The neurobiological basis of autism spectrum disorder (ASD) remains poorly understood.
Given the role of CD38 in social recognition through oxytocin (OT) release, we hypothesized …

Human CD38 is a multifunctional protein involved in diverse functions. As an enzyme, it is
responsible for the synthesis of two Ca 2+ messengers, cADPR and NAADP; as an antigen …

We previously demonstrated that cyclic ADP‐ribose (cADPR) elicits Ca2+ release in airway
smooth muscle (ASM) cells through ryanodine receptor channels. CD38 is a cell surface …

CD38/cyclic adenosine diphosphate ribose (cADPR) signaling plays an important role in the
regulation of intracellular calcium responses to agonists in a variety of cells, including airway …

The analysis of CD38 expression on lymphocytes has become an important tool for
monitoring patients during HIV-1 infection and has recently been proposed for use in the …

Here, we review the functional roles of cyclic ADP-ribose and CD38, a transmembrane
protein with ADP-ribosyl cyclase activity, in mouse social behavior via the regulation of …

Human recombinant CD38 catalyzes the formation of both cyclic ADP-ribose and ADP-
ribose products from NAD+ and hydrolyzes cyclic ADP-ribose to ADP-ribose. The …

CD38 is a nonlineage-restricted type II transmembrane glycoprotein possessing ecto-NAD+
glycohydrolase activity. Because of its unique expression pattern in lymphocyte …