[HTML][HTML] Direct and indirect cholesterol effects on membrane proteins with special focus on potassium channels
As described in the literature the interaction between cholesterol and membrane proteins
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …
can occur via direct, ligand-like and indirect mechanisms, in which cholesterol effects are …
Cyclodextrins: Only pharmaceutical excipients or full-fledged drug candidates?
Cyclodextrins, representing a versatile family of cyclic oligosaccharides, have extensive
pharmaceutical applications due to their unique truncated cone-shaped structure with a …
pharmaceutical applications due to their unique truncated cone-shaped structure with a …
Developing and testing of lipid force fields with applications to modeling cellular membranes
The amphipathic nature of the lipid molecule (hydrophilic head and hydrophobic tails)
enables it to act as a barrier between fluids with various properties and to sustain an …
enables it to act as a barrier between fluids with various properties and to sustain an …
Structure and dynamics of GPCRs in lipid membranes: physical principles and experimental approaches
Over the past decade, the vast amount of information generated through structural and
biophysical studies of GPCRs has provided unprecedented mechanistic insight into the …
biophysical studies of GPCRs has provided unprecedented mechanistic insight into the …
On the coupling between mechanical properties and electrostatics in biological membranes
VV Galassi, N Wilke - Membranes, 2021 - mdpi.com
Cell membrane structure is proposed as a lipid matrix with embedded proteins, and thus,
their emerging mechanical and electrostatic properties are commanded by lipid behavior …
their emerging mechanical and electrostatic properties are commanded by lipid behavior …
Biomembrane lipids: When physics and chemistry join to shape biological activity
F Ramos-Martín, N D'Amelio - Biochimie, 2022 - Elsevier
Biomembranes constitute the first lines of defense of cells. While small molecules can often
permeate cell walls in bacteria and plants, they are generally unable to penetrate the barrier …
permeate cell walls in bacteria and plants, they are generally unable to penetrate the barrier …
Role of lipid composition, physicochemical interactions, and membrane mechanics in the molecular actions of microbial cyclic lipopeptides
D Balleza, A Alessandrini, MJ Beltrán García - The Journal of membrane …, 2019 - Springer
Several experimental and theoretical studies have extensively investigated the effects of a
large diversity of antimicrobial peptides (AMPs) on model lipid bilayers and living cells …
large diversity of antimicrobial peptides (AMPs) on model lipid bilayers and living cells …
[HTML][HTML] Novel insights into the modulation of the voltage-gated potassium channel KV1. 3 activation gating by membrane ceramides
Membrane lipids extensively modulate the activation gating of voltage-gated potassium
channels (KV), however, much less is known about the mechanisms of ceramide and …
channels (KV), however, much less is known about the mechanisms of ceramide and …
Structure-activity relationships of mitochondria-targeted tetrapeptide pharmacological compounds
W Mitchell, JD Tamucci, EL Ng, S Liu, AV Birk… - Elife, 2022 - elifesciences.org
Mitochondria play a central role in metabolic homeostasis, and dysfunction of this organelle
underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with …
underpins the etiology of many heritable and aging-related diseases. Tetrapeptides with …
The Membrane Dipole Potential and the Roles of Interfacial Water and Lipid Hydrocarbon Chains
Understanding membrane charge transport processes, including the actions of ion
channels, pumps, carriers, and membrane-active peptides, requires a description of the …
channels, pumps, carriers, and membrane-active peptides, requires a description of the …