A systematic review of therapeutic approaches used in experimental models of interstitial cystitis/bladder pain syndrome

T Kuret, D Peskar, A Erman, P Veranič - Biomedicines, 2021 - mdpi.com
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a multifactorial, chronic bladder
disorder with limited therapeutic options currently available. The present review provides an …

[HTML][HTML] Emerging molecular mechanisms and genetic targets for developing novel therapeutic strategies for treating bladder diseases

R Zoqlam, S Lazauskaite, S Glickman… - European Journal of …, 2022 - Elsevier
Bladder diseases affect millions of patients worldwide and compromise their quality of life
with a substantial economic impact. The not fully understood aetiologies of bladder diseases …

Urinary Levels of miR-491-5p and miR-592 as Potential Diagnostic Biomarkers in Female Aging Patients with OAB: A Pilot Study

PG Cammisotto, AH Mossa, S Shamout, L Campeau - Metabolites, 2022 - mdpi.com
Women with overactive bladder syndrome (OAB) have a lower urinary ratio of nerve growth
factor (NGF) to its precursor (proNGF) compared to healthy controls. MicroRNAs related to …

[HTML][HTML] MicroRNA expression profile in the spinal cord injured rat neurogenic bladder by next-generation sequencing

Z Shang, T Ou, J Xu, H Yan, B Cui, Q Wang… - Translational …, 2020 - ncbi.nlm.nih.gov
Background An increasing amount of evidence has indicated that microRNAs (miRs) are
involved in most biological conditions, including the neurogenic bladder (NB). However, to …

Gene expression in urinary incontinence and pelvic organ prolapse: a review of literature

I Isali, J Abdeldayem, S El-Nashar - Current Opinion in Obstetrics …, 2020 - journals.lww.com
Gene expression in urinary incontinence and pelvic organ pro... : Current Opinion in
Obstetrics and Gynecology Gene expression in urinary incontinence and pelvic organ …

Comprehensive analysis of correlations in the expression of miRNA genes and immune checkpoint genes in bladder cancer cells

PA Stempor, D Avni, R Leibowitz, Y Sidi… - International Journal of …, 2021 - mdpi.com
Personalised medicine is the future and hope for many patients, including those with
cancers. Early detection, as well as rapid, well-selected treatment, are key factors leading to …

[HTML][HTML] Potential role of monocyte chemoattractant Protein-1 in monitoring disease progression and response to treatment in overactive bladder patients

G Ghoniem, B Farhan, D Csuka… - International …, 2020 - ncbi.nlm.nih.gov
Purpose To compare urinary levels of monocyte chemoattractant protein-1 (MCP-1), an
inflammatory cytokine, in healthy controls and overactive bladder (OAB) patients, to correlate …

[HTML][HTML] ADRB3, ROCK2, and GEF levels in overactive bladder patients

E Fırat, Z Aybek, H Aybek - International Neurourology Journal, 2022 - ncbi.nlm.nih.gov
Purpose The aim of this study was to evaluate changes in levels of adrenergic receptor β3
(ADRB3), Rho-related kinase 2 (ROCK2), and guanine nucleotide exchange factor (GEF) …

Polygenic risk score predicting susceptibility of female overactive bladder in the Han Chinese

SC Hung, LW Chang, GC Lin, JR Li, IC Chen - 2023 - researchsquare.com
Objective: Our study aims to explore the predictive potential of a polygenic risk score (PRS)
in overactive bladder (OAB) as well as its impact on drug compliance. Materials and …

Molecular biology, genetic, and epigenetics of bladder disease

AN Shabestari, B Fattahi, SM Ghahestani… - Genetics and Epigenetics …, 2025 - Elsevier
The bladder is one of the organs of the urinary system with a bag-like shape, whose role is
to collect urine resulting from kidney activity. The wall of the bladder is composed of muscle …