The nuclear hormone receptor (NR) superfamily includes the orphan NR4A subgroup,
comprised of Nur77 (NR4A1), Nurr1 (NR4A2) and NOR-1 (NR4A3). These NRs are …

In various physiological contexts, Nr4a genes are transcribed in response to external stimuli
as part of an immediate early response that initiates a cascade of gene expression ultimately …

Members of the nuclear receptor (NR) superfamily of transcription factors modulate gene
transcription in response to small lipophilic molecules. Transcriptional activity is regulated by …

The specification of neuronal fates in the ventral spinal cord depends on the regulation of
homeodomain (HD) and basic-helix-loop-helix (bHLH) proteins by Sonic hedgehog (Shh) …

The androgen receptor (AR) is required for male sex development and contributes to
prostate cancer cell survival. In contrast to other nuclear receptors that bind the LXXLL motifs …

Ecdysteroid pulses trigger the major developmental transitions during the Drosophila life
cycle. These hormonal responses are thought to be mediated by the ecdysteroid receptor …

NOR-1/NR4A3 is an" orphan member" of the nuclear hormone receptor superfamily. NOR-1
and its close relatives Nurr1 and Nur77 are members of the NR4A subgroup of nuclear …

In recent years, the meso-diencephalic dopaminergic (mdDA) neurons have been
extensively studied for their association with Parkinson's disease. Thus far, specification of …

Nuclear receptor related 1 (Nurr1) is a transcription factor with neuroprotective and
antineuroinflammatory properties. Observations from genetic studies and human patients …

Nur77/NR4A1 is an" orphan member" of the nuclear hormone receptor superfamily. Nur77
and its close relatives Nurr1 and NOR-1 bind as monomers to a consensus binding site, the …