Immunopathogenesis of IBD: current state of the art

HSP De Souza, C Fiocchi - Nature reviews Gastroenterology & …, 2016 - nature.com
IBD is a chronic inflammatory condition of the gastrointestinal tract encompassing two main
clinical entities: Crohn's disease and ulcerative colitis. Although Crohn's disease and …

Anti-inflammatory microRNAs and their potential for inflammatory diseases treatment

A Tahamtan, M Teymoori-Rad, B Nakstad… - Frontiers in …, 2018 - frontiersin.org
Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

IBD immunopathogenesis: a comprehensive review of inflammatory molecules

JH Park, L Peyrin-Biroulet, M Eisenhut, JI Shin - Autoimmunity reviews, 2017 - Elsevier
Inflammatory molecules play a crucial role in the pathogenesis of inflammatory bowel
disease (IBD) such as ulcerative colitis and Crohn's disease, both of which are chronic …

Semi-supervised learning for potential human microRNA-disease associations inference

X Chen, GY Yan - Scientific reports, 2014 - nature.com
MicroRNAs play critical role in the development and progression of various diseases.
Predicting potential miRNA-disease associations from vast amount of biological data is an …

The multifaceted role of the intestinal microbiota in colon cancer

T Irrazábal, A Belcheva, SE Girardin, A Martin… - Molecular cell, 2014 - cell.com
In recent years, our understanding of the mechanisms underlying colorectal carcinogenesis
has vastly expanded. Underlying inflammation within the intestine, diet, and most recently …

Beyond gene discovery in inflammatory bowel disease: the emerging role of epigenetics

NT Ventham, NA Kennedy, ER Nimmo, J Satsangi - Gastroenterology, 2013 - Elsevier
In the past decade, there have been fundamental advances in our understanding of genetic
factors that contribute to the inflammatory bowel diseases (IBDs) Crohn's disease and …

MicroRNA biomarkers in IBD—differential diagnosis and prediction of colitis-associated cancer

JP James, LB Riis, M Malham, E Høgdall… - International journal of …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) includes Crohn's disease (CD) and ulcerative colitis (UC).
These are chronic autoimmune diseases of unknown etiology affecting the gastrointestinal …

Differential intestinal anti‐inflammatory effects of Lactobacillus fermentum and Lactobacillus salivarius in DSS mouse colitis: impact on microRNAs expression and …

A Rodríguez‐Nogales, F Algieri… - Molecular nutrition & …, 2017 - Wiley Online Library
Scope To compare the intestinal anti‐inflammatory effects of two probiotics Lactobacillus
fermentum and Lactobacillus salivarius in mouse colitis, focusing on their impact on selected …

Intestinal anti-inflammatory effect of the probiotic Saccharomyces boulardii in DSS-induced colitis in mice: Impact on microRNAs expression and gut microbiota …

A Rodríguez-Nogales, F Algieri, J Garrido-Mesa… - The Journal of nutritional …, 2018 - Elsevier
The beneficial effects exerted by probiotics in inflammatory bowel disease (IBD) are well
known, although their exact mechanisms have not been fully elucidated, and only few …

The current status of molecular biomarkers for inflammatory bowel disease

Z Alghoul, C Yang, D Merlin - Biomedicines, 2022 - mdpi.com
Diagnosis and prognosis of inflammatory bowel disease (IBD)—a chronic inflammation that
affects the gastrointestinal tract of patients—are challenging, as most clinical symptoms are …