Abstract The glucagon-like peptide-1 (GLP-1) receptor, known as GLP-1R, is a vital
component of the G protein-coupled receptor (GPCR) family and is found primarily on the …

Soybeans are rich in proteins and lipids and have become a staple part of the human diet.
Besides their nutritional excellence, they have also been shown to contain various functional …

Background: Frailty is a multidimensional condition often diagnosed in older adults with
hypertension and diabetes, and both these conditions are associated with endothelial …

Background Diabetes is associated with increased fracture risk but we do not know what
affects this risk. We investigated the risk of hip and non-vertebral fractures in diabetes and …

Background Diabetes and hypertension are common in older adults and represent
established risk factors for frailty. Frailty is a multidimensional condition due to reserve loss …

OBJECTIVE We aimed to assess whether individuals with type 2 diabetes (T2D) have
increased risk of vertebral fractures (VFs) and to estimate nonvertebral fracture and mortality …

Abstract Type 2 diabetes (T2D) is associated with numerous complications, including
increased risk of fragility fractures, despite seemingly protective factors [eg, normal bone …

Skeletal muscle is the largest and most energy-consuming organ in the human body, which
plays an important role in energy metabolism and glucose uptake. There is a notable …

Background Cross-sectional studies found that frailty was associated with prevalent diabetic
microvascular complications (DMC). Longitudinal evidence in this regard is inconclusive …

Metformin, an effective hypoglycemic, can modulate different points of malignant mass,
polycystic ovary syndrome (PCOS), cardiovascular diseases, tuberculosis, and nerve …