The effect of cilia and the mucociliary clearance on successful drug delivery

S Gizurarson - Biological and Pharmaceutical Bulletin, 2015 - jstage.jst.go.jp
Nasal mucociliary clearance is one of the most important factors affecting nasal delivery of
drugs and vaccines. This is also the most important physiological defense mechanism inside …

Particularities and clinical applicability of saccharin transit time test

F Rodrigues, AP Freire, J Uzeloto… - International …, 2019 - thieme-connect.com
Introduction The importance of mucociliary clearance (MCC) for the respiratory system
homeostasis is clear. Therefore, evaluating this defense mechanism is fundamental in …

Effects of cigarette smoking intensity on the mucociliary clearance of active smokers

RF Xavier, D Ramos, JT Ito, FMM Rodrigues… - Respiration, 2014 - karger.com
Background: Smoking impairs mucociliary clearance and increases respiratory infection
frequency and severity in subjects with and without smoking-related chronic lung diseases …

Radiofrequency volume turbinate reduction versus partial turbinectomy: clinical and histological features

M Garzaro, V Landolfo, M Pezzoli… - American Journal of …, 2012 - journals.sagepub.com
Background Nasal obstruction is a common symptom related to turbinate hypertrophy in
20% of cases. When medical treatment failed different surgical options were available …

[HTML][HTML] Nasal and systemic inflammatory profile after short term smoking cessation

FMM Rodrigues, D Ramos, RF Xavier, JT Ito… - Respiratory …, 2014 - Elsevier
Introduction Smoking cessation promotes health benefits and, despite cigarette smoking be
an important pro inflammatory stimulus, there are few studies concerning the nasal and …

Effects of different mechanical ventilation strategies on the mucociliary system

VS Piccin, C Calciolari, K Yoshizaki, S Gomes… - Intensive care …, 2011 - Springer
Objective To evaluate the effects of different mechanical ventilation (MV) strategies on the
mucociliary system. Design and setting Experimental study. Subjects Twenty-seven male …

Targeting the 'garbage-bin'to fight cancer: HDAC6 inhibitor WT161 has an anti-tumor effect on osteosarcoma and synergistically interacts with 5-FU

CM Sergi - Bioscience Reports, 2021 - portlandpress.com
An imbalance between protein aggregation and protein degradation may induce 'stress' in
the functionality of the endoplasmic reticulum (ER). There are quality control (QC) …

Effect of prehydration on nasal mucociliary clearance in low relative humidity

H Oozawa, H Kimura, T Noda, K Hamada, T Morimoto… - Auris Nasus …, 2012 - Elsevier
OBJECTIVE: Nasal mucociliary clearance, which plays an important role in defending the
respiratory system, tends to decrease under conditions of low relative humidity (RH). The …

Методические подходы к комплексному изучению функциональной морфологии эпителиальной выстилки трахеи в эксперименте

АВ Павлов, ЛИ Есев - Морфология, 2012 - elibrary.ru
Описан алгоритм функционального и морфологического анализа трахеи мелких
лабораторных животных, включающий последовательное изучение скорости движения …

[HTML][HTML] Analysis of the sputum and inflammatory alterations of the airways in patients with common variable immunodeficiency and bronchiectasis

AC Pereira, CM Kokron, BMS Romagnolo, CSA Yagi… - Clinics, 2009 - SciELO Brasil
INTRODUCTION: Common variable immunodeficiency is characterized by defective
antibody production and recurrent pulmonary infections. Intravenous immunoglobulin is the …