Metaproteome and metabolome of oral microbial communities

N Bostanci, M Grant, K Bao, A Silbereisen… - Periodontology …, 2021 - Wiley Online Library
The emergence of high‐throughput technologies for the comprehensive measurement of
biomolecules, also referred to as “omics” technologies, has helped us gather “big data” and …

Structural biology of calcium phosphate nanoclusters sequestered by phosphoproteins

S Lenton, Q Wang, T Nylander, S Teixeira, C Holt - Crystals, 2020 - mdpi.com
Biofluids that contain stable calcium phosphate nanoclusters sequestered by
phosphopeptides make it possible for soft and hard tissues to co-exist in the same organism …

Top-down proteomics of human saliva highlights anti-inflammatory, antioxidant, and antimicrobial defense responses in alzheimer disease

C Contini, A Olianas, S Serrao, C Deriu… - Frontiers in …, 2021 - frontiersin.org
Alzheimer disease (AD) is the most prevalent neurodegenerative disease in the elderly,
characterized by accumulation in the brain of misfolded proteins, inflammation, and …

The intriguing heterogeneity of human salivary proline-rich proteins: Short title: Salivary proline-rich protein species

B Manconi, M Castagnola, T Cabras, A Olianas… - Journal of …, 2016 - Elsevier
The most heterogeneous family of human salivary proteins is represented by proline-rich
proteins (PRPs) divided in acidic, basic, and basic glycosylated (aPRPs, bPRPs, gPRPs) …

Top-down proteomic profiling of human saliva in multiple sclerosis patients

B Manconi, B Liori, T Cabras, F Vincenzoni… - Journal of …, 2018 - Elsevier
Multiple sclerosis is a chronic disease of the central nervous system characterized by
inflammation, demyelination and neurodegeneration which is of undetermined origin. To …

A top‐down proteomic approach reveals a salivary protein profile able to classify Parkinson's disease with respect to Alzheimer's disease patients and to healthy …

C Contini, L Fadda, G Lai, C Masala, A Olianas… - …, 2024 - Wiley Online Library
Parkinson's disease (PD) is a complex neurodegenerative disease with motor and non‐
motor symptoms. Diagnosis is complicated by lack of reliable biomarkers. To individuate …

Metabolomics in neonatology: fact or fiction?

V Fanos, J Van den Anker, A Noto, M Mussap… - Seminars in Fetal and …, 2013 - Elsevier
The newest 'omics' science is metabolomics, the latest offspring of genomics, considered the
most innovative of the 'omics' sciences. Metabolomics, also called the 'new clinical …

Characterization of salivary proteins of schizophrenic and bipolar disorder patients by top-down proteomics

F Iavarone, M Melis, G Platania, T Cabras… - Journal of …, 2014 - Elsevier
The analysis of whole saliva of 32 subjects with diagnosis of schizophrenia (SZ), 17 with
diagnosis of bipolar disorder (BD), and 31 healthy subjects divided in non-smokers (HN; n …

Quantitative analysis of human salivary gland‐derived intact proteome using top‐down mass spectrometry

S Wu, JN Brown, N Tolić, D Meng, X Liu, H Zhang… - …, 2014 - Wiley Online Library
There are several notable challenges inherent for fully characterizing the entirety of the
human saliva proteome using bottom‐up approaches, including polymorphic isoforms, PTM …

Standardization of a protocol for shotgun proteomic analysis of saliva

TMS Ventura, NR Ribeiro, AS Dionizio… - Journal of Applied Oral …, 2018 - SciELO Brasil
Saliva contains numerous proteins and peptides, each of them carries a number of
biological functions that are very important in maintaining the oral cavity health and also …