Hyperuricemia and its related diseases: mechanisms and advances in therapy

L Du, Y Zong, H Li, Q Wang, L Xie, B Yang… - … and Targeted Therapy, 2024 - nature.com
Hyperuricemia, characterized by elevated levels of serum uric acid (SUA), is linked to a
spectrum of commodities such as gout, cardiovascular diseases, renal disorders, metabolic …

Isorhamnetin, the xanthine oxidase inhibitor from Sophora japonica, ameliorates uric acid levels and renal function in hyperuricemic mice

F Wang, X Zhao, X Su, D Song, F Zou, L Fang - Food & Function, 2021 - pubs.rsc.org
Hyperuricemia is a metabolic condition closely linked to xanthine oxidase (XOD) function,
which is involved in the production of uric acid (UA). In this study, XOD was used as a target …

Dietary supplementation of l-carnitine ameliorates metabolic syndrome independent of trimethylamine N-oxide produced by gut microbes in high-fat diet-induced …

X Gao, C Sun, Y Zhang, S Hu, D Li - Food & Function, 2022 - pubs.rsc.org
Metabolic syndrome (MS) is a collection of risk factors of serious metabolic diseases. L-
Carnitine is an essential nutrient for human health, and the precursor of trimethylamine N …

[HTML][HTML] Causal inference of carnitine on blood pressure and potential mediation by uric acid: a Mendelian randomization analysis

MA Richard, PJ Lupo, JP Zachariah - International Journal of Cardiology …, 2021 - Elsevier
Background Dietary change alters blood pressure (BP) but the specific causal dietary
elements are unclear. Given previous observational data suggesting serum carnitine or uric …

Метаболический синдром у детей и подростков: современное состояние проблемы. Педиатрия

ЕС Самошкина, ЛА Балыкова, АА Широкова… - Журнал им. ГН …, 2022 - elibrary.ru
В обзоре литературы представлены современные данные о метаболическом
синдроме у детей и подростков, критериях его диагностики и ассоциированной с ним …

Zingerone administered neonatally prevents the subsequent development of high dietary fructose-induced fatty liver in sprague dawley rats

N Muhammad, BW Lembede… - Journal of Medicinal …, 2021 - liebertpub.com
Consumption of high-fructose diets early in life increases the risk of developing metabolic
disorders, including nonalcoholic fatty liver disease (NAFLD). Zingerone, an alkaloid …

Association between urinary phthalate metabolites and hyperuricemia in US adults

H Wang, Y Cui, F Zhang, R Song, L Zhao… - … Science and Pollution …, 2023 - Springer
Phthalate metabolites have been detected from urine in most of the US population and have
become a public health problem. However, the association between phthalate metabolites …

Effects of fructose-induced metabolic syndrome on kidney histology in rats

Ö Güleş, M Tatar - Kocatepe Veterinary Journal, 2020 - dergipark.org.tr
Metabolic syndrome is a fatal endocrinopathy, which is progressed towards pandemic, and
characterized by insulin resistance, abdominal obesity, dyslipidemia, diabetes mellitus …

[PDF][PDF] Neonatal administration of zingerone prevents the subsequent development of high dietary fructose-induced early features of nephropathy in rats.

N Muhammad, BW Lembede… - General Physiology & …, 2022 - wiredspace.wits.ac.za
Excessive consumption of fructose-rich diets in early life stages increases the risk for
developing nephropathy in adulthood. We investigated the potential preventive effects of …

[PDF][PDF] CHAPTER FOUR-Published manuscript 2 Zingerone administered neonatally prevents the subsequent development of high dietary fructose-induced fatty liver …

N Muhammad, BW Lembede… - THE POTENTIAL OF …, 2020 - wiredspace.wits.ac.za
Consumption of high-fructose diets early in life increases the risk of developing metabolic
disorders, including non-alcoholic fatty liver disease (NAFLD). Zingerone, an alkaloid …