Negative social experiences during adolescence are central features for several stress- related mental illnesses. Social play fighting behavior in rats peaks during early …
The fear circuitry orchestrates defense mechanisms in response to environmental threats. This circuitry is evolutionarily crucial for survival, but its dysregulation is thought to play a …
Serotonin (5-HT) is an ancient molecule directing behavioural responses to environmental stimuli. The social environment is the most powerful environmental factor. It is well …
M Serra-Millàs - World journal of psychiatry, 2016 - ncbi.nlm.nih.gov
Brain-derived neurotrophic factor (BDNF) plays an important role in central nervous system development, neurogenesis and neuronal plasticity. BDNF is also expressed in several non …
Exposure to adverse experiences in early-life is implicated in the later vulnerability to development of psychiatric disorders, including anxiety and affective disorders in humans …
The in vivo study of receptor binding potential in the human brain is made possible by positron emission tomography (PET) imaging. Here we review PET studies of neuroreceptor …
KA van Galen, KW Ter Horst, J Booij, SE la Fleur… - Metabolism, 2018 - Elsevier
Obesity results from an imbalance between energy intake and expenditure, and many studies have aimed to determine why obese individuals continue to (over) consume food …
RV Parsey, RT Ogden, JM Miller, A Tin… - Biological …, 2010 - Elsevier
BACKGROUND: Serotonin 1A receptors (5-HT1A) are implicated in major depressive disorder (MDD). We previously reported higher 5-HT1A binding potential (BPF) in …
T Renoir - Frontiers in Pharmacology, 2013 - frontiersin.org
Besides demonstrated efficacy, selective serotonin reuptake inhibitors (SSRIs) hold other advantages over earlier antidepressants such as greater tolerability and a wider range of …