Despite the fact that MRI has evolved to become the standard method for diagnosis and
monitoring of patients with brain tumours, conventional MRI sequences have two key …

Metabolomics, a science of systems biology, is the global assessment of endogenous
metabolites within a biologic system and represents a “snapshot” reading of gene function …

BACKGROUND AND PURPOSE: Atypical and malignant meningiomas are uncommon
tumors with aggressive behavior and higher mortality, morbidity, and recurrence compared …

At present, a radical shift in cancer treatment is occurring in terms of predictive, preventive,
and personalized medicine (PPPM). Individual patients will participate in more aspects of …

The adaptability and the genomic plasticity of cancer cells, and the interaction between the
tumor microenvironment and co-opted stromal cells, coupled with the ability of cancer cells …

The collection of global metabolic data and their interpretation (both spectral and
biochemical) using modern spectroscopic techniques and appropriate statistical …

Choline phospholipid metabolism is altered in a wide variety of cancers. The choline
metabolite profile of tumors and cancer cells is characterized by an elevation of …

Since its discovery in the 1940s, magnetic resonance spectroscopy (MRS) has developed
into a major technique used by chemists to elucidate molecular structures. The underlying …

Background Rectal cancer is one of the most prevalent tumor types. Understanding the
metabolic profile of rectal cancer is important for developing therapeutic approaches and …

BACKGROUND AND PURPOSE: Noninvasive grading of gliomas remains a challenge
despite its important role in the prognosis and management of patients with intracranial …