Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes

JR Huddleston - Infection and drug resistance, 2014 - Taylor & Francis
Bacterial infections are becoming increasingly difficult to treat due to widespread antibiotic
resistance among pathogens. This review aims to give an overview of the major horizontal …

Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

I Chopra, M Roberts - Microbiology and molecular biology reviews, 2001 - Am Soc Microbiol
Tetracyclines were discovered in the 1940s and exhibited activity against a wide range of
microorganisms including gram-positive and gram-negative bacteria, chlamydiae …

Bacteroides: the Good, the Bad, and the Nitty-Gritty

HM Wexler - Clinical microbiology reviews, 2007 - Am Soc Microbiol
Summary: Bacteroides species are significant clinical pathogens and are found in most
anaerobic infections, with an associated mortality of more than 19%. The bacteria maintain a …

Integrative and conjugative elements: mosaic mobile genetic elements enabling dynamic lateral gene flow

RAF Wozniak, MK Waldor - Nature Reviews Microbiology, 2010 - nature.com
Integrative and conjugative elements (ICEs) are a diverse group of mobile genetic elements
found in both Gram-positive and Gram-negative bacteria. These elements primarily reside in …

Mobile genetic elements: the agents of open source evolution

LS Frost, R Leplae, AO Summers… - Nature Reviews …, 2005 - nature.com
Horizontal genomics is a new field in prokaryotic biology that is focused on the analysis of
DNA sequences in prokaryotic chromosomes that seem to have originated from other …

Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste

JC Chee‐Sanford, RI Mackie, S Koike… - Journal of …, 2009 - Wiley Online Library
Antibiotics are used in animal livestock production for therapeutic treatment of disease and
at subtherapeutic levels for growth promotion and improvement of feed efficiency. It is …

Potential impacts of disinfection processes on elimination and deactivation of antibiotic resistance genes during water and wastewater treatment

MC Dodd - Journal of Environmental Monitoring, 2012 - pubs.rsc.org
Antibiotic resistance genes (ARGs), in association with antibiotic resistant bacteria (ARB),
have been identified as widespread contaminants of treated drinking waters and …

Resistance in the environment

K Kümmerer - Journal of antimicrobial chemotherapy, 2004 - academic.oup.com
Antibiotics, disinfectants and bacteria resistant to them have been detected in environmental
compartments such as waste water, surface water, ground water, sediments and soils …

Bacterial genome instability

E Darmon, DRF Leach - Microbiology and Molecular Biology …, 2014 - Am Soc Microbiol
Bacterial genomes are remarkably stable from one generation to the next but are plastic on
an evolutionary time scale, substantially shaped by horizontal gene transfer, genome …

Antibiotic resistance in food lactic acid bacteria—a review

S Mathur, R Singh - International journal of food microbiology, 2005 - Elsevier
Antibiotics are a major tool utilized by the health care industry to fight bacterial infections;
however, bacteria are highly adaptable creatures and are capable of developing resistance …