Application of mathematical expectation (ME) strategy for detecting low frequency mutations: An example for evaluating 14-bp insertion/deletion (indel) within the …

Q Yang, S Zhang, L Liu, X Cao, C Lei, X Qi, F Lin, W Qu… - Prion, 2016 - Taylor & Francis
The detection method based on the mathematical expectation (ME) strategy is fast and
accuracy for low frequency mutation screening in large samples. Previous studies have …

Structure of the prion protein and its gene: an analysis using bioinformatics and computer simulation

A Sakudo, G Xue, N Kawashita, Y Ano… - Current Protein and …, 2010 - ingentaconnect.com
Prion protein (PrP) gene encodes cellular PrP (PrPC), a glycosylphosphatidylinositol (GPI)-
anchored cell membrane protein indispensable for infections of prion, which causes …

A 20-bp insertion/deletion (indel) polymorphism within the CDC25A gene and its associations with growth traits in goat

W Cui, N Liu, X Zhang, Y Zhang, L Qu… - Archives Animal …, 2019 - aab.copernicus.org
Cell division cycle 25A (CDC25A), a member of the CDC25 family of phosphatases, is
required for progression from G1 to the S phase of the cell cycle. CDC25A provides an …

PRNP gene variation in Pakistani cattle and buffaloes

M Imran, S Mahmood, ME Babar, R Hussain… - Gene, 2012 - Elsevier
Bovine spongiform encephalopathy (BSE) is a neurodegenerative prion protein misfolding
disorder of cattle. BSE is of two types, classical BSE and atypical BSE which in turn is of two …

Coordinate regulation of bovine prion protein gene promoter activity by two Sp1 binding site polymorphisms

G Xue, A Sakudo, C Kim, T Onodera - Biochemical and biophysical …, 2008 - Elsevier
Relationships between insertion/deletion (Ins/Del) polymorphisms of the bovine prion
protein gene (PRNP) promoter and bovine spongiform encephalopathy (BSE) susceptibility …

The 5′ Flanking Region and Intron1 of the Bovine Prion Protein Gene (PRNP) Are Responsible for Negative Feedback Regulation of the Prion Protein

G Xue, Y Aida, T Onodera, A Sakudo - Plos one, 2012 - journals.plos.org
Transcription factors regulate gene expression by controlling the transcription rate. Some
genes can repress their own expression to prevent over production of the corresponding …

The evaluation of 23-bp and 12-bp insertion/deletion within the PRNP gene and their effects on growth traits in healthy Chinese native cattle breeds

Q Yang, S Zhang, L Liu, C Lei, X Qi, F Lin… - Journal of Applied …, 2018 - Taylor & Francis
Polymorphisms in the prion protein gene (PRNP) have been linked with the occurrence of
transmissible spongiform encephalopathies and the expression of some phenotypic traits in …

Examination of a regulatory SNP of bovine RCAN2 gene in transgenic mouse model.

S Gabriella, K Andrea, HO Ivett, B Endre, D Rocha… - 2013 - cabidigitallibrary.org
We examined numerous regulatory single-nucleotid-polymorphisms (rSNP) of bovine genes
with economically important traits in transgenic mouse models. After bioinformatical studies …

[引用][C] Analysis of the PRNP gene expression based on genotypes for the indel23pb and indel12pb polymorphisms in cervical spinal cord and palatine tonsils of …

R Artigas, P Nicolini, N Vazquez… - … DEL GEN PRNP … - Universidad de la República