Diffusion MRI uses the random displacement of water molecules to sensitize the signal to
brain microstructure and to properties such as the density and shape of cells. Microstructure …

Traumatic brain injury (TBI) is a complex condition that can resolve over time but all too often
leads to persistent symptoms, and the risk of poor patient outcomes increases with aging …

United States (US) Special Operations Forces (SOF) are frequently exposed to explosive
blasts in training and combat, but the effects of repeated blast exposure (RBE) on SOF brain …

There is increased interest in developing markers reflecting microstructural changes that
could serve as outcome measures in clinical trials. This is especially important after …

The relationship between brain microstructure and aging has been the subject of intense
study, with diffusion MRI perhaps the most effective modality for elucidating these …

Human evolution has seen the development of higher-order cognitive and social capabilities
in conjunction with the unique laminar cytoarchitecture of the human cortex. Moreover, early …

Diffusion MRI with free gradient waveforms, combined with simultaneous relaxation
encoding, referred to as multidimensional MRI (MD‐MRI), offers microstructural specificity in …

Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of RCC,
and accurate grading is crucial for prognosis and treatment selection. Biopsy is the …

Astrocytes are in contact with the vasculature, neurons, oligodendrocytes and microglia,
forming a local network with various functions critical for brain homeostasis. One of the …

Chronic traumatic encephalopathy is a neurodegenerative disease that is diagnosed and
staged based on the localization and extent of phosphorylated tau pathology. Although its …