Bubble columns are used in many different industrial applications, and their design and
characterisation have always been very complex. In recent years, the use of Computational …

Computational fluid dynamics (CFD) is a widely used tool for investigating fluid flows in
bioreactors. It has been used in the biopharmaceutical industry for years and has …

Industrial aerobic fermentation processes are performed in large-scale bioreactors (> 20 m
3). Understanding the local values of the velocity field, the eddy dissipation rate and the gas …

In the current study, Artificial Intelligence (AI) approach was used for the learning of a
physical system. We applied four inputs and one output in the learning process of AI. In the …

We have examined the effect of superficial velocity, tracer injection location and
measurement location on the mixing time in a bubble column. It was found that for the range …

The underlying mechanism and the generality of the drag correction factor CD/C D0, which
was developed and applied in the simulation of bubble columns at elevated pressure in our …

Bubble columns are used in many industrial applications, but the complex fluid dynamics
phenomena has limited their design and optimization processes. Computational Fluid …

Although bubble columns are widely used in many industrial situations, there are very few
studies of such devices operating at high superficial velocities. Numerical simulations using …

The production rate of fed-batch aerobic fermenters is often limited by the oxygen transfer
rate that depends on the fluid dynamics of the gas-liquid system. In turn, ideal flow regimes …

Unsteady and three-dimensional Eulerian–Eulerian CFD simulations of bubble column
reactors under operating conditions of industrial interest are discussed in this work. The flow …