The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
This review summarizes the distinct immune mechanisms implicated in preterm labor and …
Placental pathology is necessary to understand common pregnancy complications and achieve an improved taxonomy of obstetrical disease
RW Redline, DJ Roberts, MM Parast, LM Ernst… - American journal of …, 2023 - Elsevier
The importance of a fully functioning placenta for a good pregnancy outcome is
unquestioned. Loss of function can lead to pregnancy complications and is often detected by …
unquestioned. Loss of function can lead to pregnancy complications and is often detected by …
Deciphering maternal-fetal cross-talk in the human placenta during parturition using single-cell RNA sequencing
Labor is a complex physiological process requiring a well-orchestrated dialogue between
the mother and fetus. However, the cellular contributions and communications that facilitate …
the mother and fetus. However, the cellular contributions and communications that facilitate …
Clinical chorioamnionitis at term X: microbiology, clinical signs, placental pathology, and neonatal bacteremia–implications for clinical care
Objectives Clinical chorioamnionitis at term is considered the most common infection-related
diagnosis in labor and delivery units worldwide. The syndrome affects 5–12% of all term …
diagnosis in labor and delivery units worldwide. The syndrome affects 5–12% of all term …
[HTML][HTML] RNA sequencing reveals diverse functions of amniotic fluid neutrophils and monocytes/macrophages in intra-amniotic infection
Intra-amniotic infection, the invasion of microbes into the amniotic cavity resulting in
inflammation, is a clinical condition that can lead to adverse pregnancy outcomes for the …
inflammation, is a clinical condition that can lead to adverse pregnancy outcomes for the …
RNA sequencing reveals distinct immune responses in the chorioamniotic membranes of women with preterm labor and microbial or sterile intra-amniotic …
Preterm labor precedes premature birth, the leading cause of neonatal morbidity and
mortality worldwide. Preterm labor can occur in the context of either microbe-associated intra …
mortality worldwide. Preterm labor can occur in the context of either microbe-associated intra …
Cadmium induced inflammation and apoptosis of porcine epididymis via activating RAF1/MEK/ERK and NF-κB pathways
Y Zhang, Y Li, J Zhang, X Qi, Y Cui, K Yin… - Toxicology and Applied …, 2021 - Elsevier
Cadmium (Cd) was a serious heavy metal pollutant. Cd exposure will cause damage to
reproductive organs. It was largely unknown whether Cd exposure caused inflammation and …
reproductive organs. It was largely unknown whether Cd exposure caused inflammation and …
The role of innate immune system in the human amniotic membrane and human amniotic fluid in protection against intra-amniotic infections and inflammation
Intra-amniotic infection and inflammation (IAI) affect fetal development and are highly
associated with preterm labor and premature rupture of membranes, which often lead to …
associated with preterm labor and premature rupture of membranes, which often lead to …
Identification of protein biomarkers associated with congenital diaphragmatic hernia in human amniotic fluid
Congenital diaphragmatic hernia (CDH) is a severe birth defect frequently associated with
pulmonary hypoplasia, pulmonary hypertension, and heart failure. Since amniotic fluid …
pulmonary hypoplasia, pulmonary hypertension, and heart failure. Since amniotic fluid …
Intra-amniotic infection and sterile intra-amniotic inflammation are associated with elevated concentrations of cervical fluid interleukin-6 in women with spontaneous …
J Stranik, M Kacerovsky, C Andrys… - The Journal of …, 2022 - Taylor & Francis
Objective To determine the concentration of interleukin-6 (IL-6) in the cervical fluid in women
with spontaneous preterm labor with intact fetal membranes (PTL) complicated by intra …
with spontaneous preterm labor with intact fetal membranes (PTL) complicated by intra …