Nanotherapeutics for pulmonary drug delivery: An emerging approach to overcome respiratory diseases

E Kole, K Jadhav, N Shirsath, P Dudhe… - Journal of Drug Delivery …, 2023 - Elsevier
Pulmonary diseases pose an immense threat to global health. Several nanotherapeutics-
based approaches aimed to tackle pulmonary ailments in recent years. The current …

Potential of dry powder inhalers for tuberculosis therapy: facts, fidelity and future

P Mehta, C Bothiraja, S Kadam… - … cells, nanomedicine, and …, 2018 - Taylor & Francis
Tuberculosis (TB) is a contagious and airborne infectious disease caused by the pathogen
Mycobacterium tuberculosis (Mtb). In spite of substantial research efforts, continuous …

Inhalable solid lipid nanoparticles for intracellular tuberculosis infection therapy: macrophage-targeting and pH-sensitive properties

C Ma, M Wu, W Ye, Z Huang, X Ma, W Wang… - Drug Delivery and …, 2021 - Springer
Mycobacterium tuberculosis (MTB) is one of the most threatening pathogens for its latent
infection in macrophages. The intracellular MTB isolated itself from drugs and could spread …

An inhalable theranostic system for local tuberculosis treatment containing an isoniazid loaded metal organic framework Fe-MIL-101-NH2—from raw MOF to drug …

G Wyszogrodzka-Gaweł, P Dorożyński, S Giovagnoli… - Pharmaceutics, 2019 - mdpi.com
The theranostic approach to local tuberculosis treatment allows drug delivery and imaging of
the lungs for a better control and personalization of antibiotic therapy. Metal-organic …

Dry powder inhalable formulations for anti-tubercular therapy

T Parumasivam, RYK Chang, S Abdelghany… - Advanced drug delivery …, 2016 - Elsevier
Tuberculosis (TB) is an intracellular infectious disease caused by the airborne bacterium,
Mycobacterium tuberculosis. Despite considerable research efforts, the treatment of TB …

Microencapsulated solid lipid nanoparticles as a hybrid platform for pulmonary antibiotic delivery

DP Gaspar, MM Gaspar, CV Eleuterio… - Molecular …, 2017 - ACS Publications
Solid lipid nanoparticles (SLN) containing rifabutin (RFB), with pulmonary administration
purposes, were developed through a technique that avoids the use of organic solvents or …

A novel dry powder inhalable formulation incorporating three first-line anti-tubercular antibiotics

JGY Chan, HK Chan, CA Prestidge, JA Denman… - European Journal of …, 2013 - Elsevier
Treatment for tuberculosis (TB) using the standard oral antibiotic regimen is effective but
inefficient, requiring high drug dosing and lengthy treatment times. Three concurrent first-line …

Exploring inhalable polymeric dry powders for anti-tuberculosis drug delivery

MS Miranda, MT Rodrigues, RMA Domingues… - Materials Science and …, 2018 - Elsevier
The growing interest on polymeric delivery systems for pulmonary administration of drugs
anticipates a more direct and efficient treatment of diseases such as tuberculosis (TB) that …

Dry powder antibiotic aerosol product development: inhaled therapy for tuberculosis

AJ Hickey, A Misra, PB Fourie - Journal of pharmaceutical sciences, 2013 - Elsevier
Inhaled therapies offer a unique approach to the treatment of tuberculosis (TB) using a
relevant target organ system as a route of administration. The number of research reports on …

Cationic inhalable particles for enhanced drug delivery to M. tuberculosis infected macrophages

PR Sharma, AA Dravid, YC Kalapala, VK Gupta… - Biomaterials …, 2022 - Elsevier
Inhalable microparticle-based drug delivery platforms are being investigated extensively for
Tuberculosis (TB) treatment as they offer efficient deposition in lungs and improved …