The field of single-cell genomics is advancing rapidly and is generating many new insights
into complex biological systems, ranging from the diversity of microbial ecosystems to the …

The commonly existing cellular heterogeneity plays a critical role in biological processes
such as embryonic development, cell differentiation, and disease progress. Single‐cell …

Massively parallel single-cell genome sequencing is required to further understand genetic
diversities in complex biological systems. Whole genome amplification (WGA) is the first step …

Recent advances in methods for single-cell analyses and barcoding strategies have led to
considerable progress in research. The development of multiplexed assays offers the …

Microfluidic methods for barcoding nucleic acid target molecules to be analyzed, eg, via
nucleic acid sequencing techniques, are provided. Also provided are microfluidic, droplet …

Biochemical analysis is crucial in understanding mechanism of life activities and giving
biological insights into life process. With inherent merits in flexible design, microscale of …

Single-cell genomics is applied to environmental samples as a method to solve the
problems of current metagenomics. However, in the fluorescence-activated cell sorting …

This article reviews recent developments in droplet microfluidics enabling high-throughput
single-cell analysis. Five key aspects in this field are included in this review:(1) prototype …

Single-cell genomics is a straightforward approach to obtain genomes from uncultured
microbes. However, sequence reads from a single-cell amplified genome (SAG) contain …

The advent of next-generation sequencing technologies has facilitated the acquisition of
large amounts of DNA sequence data at a relatively low cost, leading to numerous …