Telomeres: New players in immune-mediated inflammatory diseases?

AC Heba, S Toupance, D Arnone… - Journal of …, 2021 - Elsevier
Telomeres are repetitive DNA sequences located at the ends of linear chromosomes that
preserve the integrity and stability of the genome. Telomere dysfunctions due to short …

The role of extracellular DNA in COVID-19: Clues from inflamm-aging

G Storci, F Bonifazi, P Garagnani, F Olivieri… - Ageing Research …, 2021 - Elsevier
Epidemiological data convey severe prognosis and high mortality rate for COVID-19 in
elderly men affected by age-related diseases. These subjects develop local and systemic …

Prenatal toxic metal mixture exposure and newborn telomere length: modification by maternal antioxidant intake

W Cowell, E Colicino, E Tanner… - Environmental …, 2020 - Elsevier
Background Telomere length (TL) predicts the onset of cellular senescence and correlates
with longevity and age-related disease risk. While telomeres erode throughout life, adults …

Acculturative stress, telomere length, and postpartum depression in Latinx mothers

ACI Rodriguez, JJ Polcari, BC Nephew, R Harris… - Journal of psychiatric …, 2022 - Elsevier
Latinx mothers in the United States are highly vulnerable to psychosocial stressors,
including discrimination and acculturative stress, which increase maternal health risks …

Associations among temperament characteristics and telomere length and attrition rate in early childhood.

M Bosquet Enlow, I De Vivo, CR Petty… - Developmental …, 2023 - psycnet.apa.org
There is growing interest in telomere length as an indicator of current and future health.
Although early childhood is a period of rapid telomere attrition, little is known about the …

Mixture effects of prenatal exposure to per-and polyfluoroalkyl substances and polybrominated diphenyl ethers on maternal and newborn telomere length

SM Eick, DE Goin, L Cushing, E DeMicco, JS Park… - Environmental …, 2021 - Springer
Background Per-and polyfluoroalkyl substances (PFAS) and polybrominated diphenyl
ethers (PBDEs) are endocrine disrupting chemicals with widespread exposures across the …

[HTML][HTML] Child buccal telomere length and mitochondrial DNA content as biomolecular markers of ageing in association with air pollution

P Hautekiet, TS Nawrot, BG Janssen, DS Martens… - Environment …, 2021 - Elsevier
Background Pro-inflammatory conditions such as air pollution might induce biological
ageing. However, the available evidence on such an impact in children is still very scarce …

Analysis of leukocyte and sperm telomere length in oligozoospermic men

M Amirzadegan, N Sadeghi, M Tavalaee… - Andrologia, 2021 - Wiley Online Library
Telomere length is considered one of the most relevant biological markers of genomic
stability since it protects DNA from impairment and also ensures chromosome alignment …

Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study

C Törn, X Liu, S Onengut-Gumuscu, KM Counts… - Scientific Reports, 2022 - nature.com
Abstract The Environmental Determinants of Diabetes in the Young (TEDDY) study enrolled
8676 children, 3–4 months of age, born with HLA-susceptibility genotypes for islet …

Associations of four biological age markers with child development: A multi-omic analysis in the European HELIX cohort

O Robinson, CHE Lau, S Joo, S Andrusaityte, E Borras… - Elife, 2023 - elifesciences.org
Background: While biological age in adults is often understood as representing general
health and resilience, the conceptual interpretation of accelerated biological age in children …