[HTML][HTML] Emerging concepts of miRNA therapeutics: from cells to clinic
MicroRNAs (miRNAs) are very powerful genetic regulators, as evidenced by the fact that a
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …
single miRNA can direct entire cellular pathways via interacting with a broad spectrum of …
RNAi-based therapeutics and tumor targeted delivery in cancer
Over the past decade, non-coding RNA-based therapeutics have proven as a great potential
for the development of targeted therapies for cancer and other diseases. The discovery of …
for the development of targeted therapies for cancer and other diseases. The discovery of …
Artificial intelligence in cancer target identification and drug discovery
Artificial intelligence is an advanced method to identify novel anticancer targets and discover
novel drugs from biology networks because the networks can effectively preserve and …
novel drugs from biology networks because the networks can effectively preserve and …
miRNet 2.0: network-based visual analytics for miRNA functional analysis and systems biology
Abstract miRNet is an easy-to-use, web-based platform designed to help elucidate
microRNA (miRNA) functions by integrating users' data with existing knowledge via network …
microRNA (miRNA) functions by integrating users' data with existing knowledge via network …
Comprehensive analysis of microRNA (miRNA) in cancer cells
N Kanwal, OR Al Samarrai, HMH Al-Zaidi… - Cellular, Molecular …, 2023 - cmbr-journal.com
MicroRNAs (miRNA) are a group of small non-coding RNAs that regulate gene expression
at the RNA level. MicroRNAs have positive regulatory effects on protein translation …
at the RNA level. MicroRNAs have positive regulatory effects on protein translation …
miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplay
Cervical cancer (CC) is the primary cause of cancer deaths in underdeveloped countries.
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …
The persistence of infection with high-risk human papillomavirus (HPV) is a significant …
Challenges identifying efficacious miRNA therapeutics for cancer
M Segal, FJ Slack - Expert opinion on drug discovery, 2020 - Taylor & Francis
MicroRNAs are a class of small non-coding RNAs (22-23 nucleotides), which regulate gene
expression at the posttranscriptional level and play key roles in tumorigenesis and other …
expression at the posttranscriptional level and play key roles in tumorigenesis and other …
The miRNA–target interactions: An underestimated intricacy
MicroRNAs (miRNAs) play indispensable roles in posttranscriptional gene regulation. Their
cellular regulatory impact is determined not solely by their sheer number, which likely …
cellular regulatory impact is determined not solely by their sheer number, which likely …
Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …
Defining disease-related modules based on weighted miRNA synergistic network
MicroRNAs (miRNAs) play an important role in the biological process. Their expression and
functional changes have been observed in most cancers. Meanwhile, there exists …
functional changes have been observed in most cancers. Meanwhile, there exists …