[HTML][HTML] Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic …

A Borrelli, P Bonelli, FM Tuccillo, ID Goldfine, JL Evans… - Redox biology, 2018 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) represents the most common chronic liver disease
in industrialized countries. NAFLD progresses through the inflammatory phase of non …

Oxidative stress in alcoholic liver disease, focusing on proteins, nucleic acids, and lipids: A review

W Lai, J Zhang, J Sun, T Min, Y Bai, J He, H Cao… - International Journal of …, 2024 - Elsevier
Oxidative stress is one of the important factors in the development of alcoholic liver disease.
The production of reactive oxygen species and other free radicals is an important feature of …

The structure–function relationships and physiological roles of MnSOD mutants

R Bonetta Valentino - Bioscience Reports, 2022 - portlandpress.com
In this review, we focus on understanding the structure–function relationships of numerous
manganese superoxide dismutase (MnSOD) mutants to investigate the role that various …

Current, emerging, and potential therapies for non-alcoholic steatohepatitis

Z Yang, L Wang - Frontiers in Pharmacology, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) has been identified as the most common chronic
liver disease worldwide, with a growing incidence. NAFLD is considered the hepatic …

Endless Dirac nodal lines and high mobility in kagome semimetal Ni3In2Se2: a theoretical and experimental study

SK Pradhan, S Pradhan, P Mal… - Journal of Physics …, 2024 - iopscience.iop.org
Kagome-lattice crystal is crucial in quantum materials research, exhibiting unique transport
properties due to its rich band structure and the presence of nodal lines and rings. Here, we …

Effects of antioxidants on apoptosis induced by dasatinib and nilotinib in K562 cells

S Damiano, S Montagnaro, MV Puzio… - Journal of Cellular …, 2018 - Wiley Online Library
In clinical practice for the treatment of chronic myeloid leukemia, second generation of
tyrosine kinase inhibitors such as Nilotinib (NIL) specific and potent inhibitor of the BCR/ABL …

Innexin hemichannel activation by Microplitis bicoloratus ecSOD monopolymer reduces ROS

JH Meng, YB Huang, J Long, QC Cai, X Qiao… - Iscience, 2024 - cell.com
The extracellular superoxide dismutases (ecSODs) secreted by Microplitis bicoloratus
reduce the reactive oxygen species (ROS) stimulated by the Microplitis bicoloratus …

Prolonged activity of a recombinant manganese superoxide dismutase through a formulation of polymeric multi-layer nanoassemblies targeting cancer cells

G Russo, G Iaccarino, M Piccolo, MG Ferraro… - European Journal of …, 2021 - Elsevier
A new isoform of human manganese superoxide dismutase (SOD) has been recently
isolated and obtained in a synthetic recombinant form and termed rMnSOD. As compared to …

A Gel Formulation Containing a New Recombinant Form of Manganese Superoxide Dismutase: A Clinical Experience Based on Compassionate Use‐Safety of a …

L Grumetto, AD Prete, G Ortosecco… - Case Reports in …, 2016 - Wiley Online Library
Background. We report a case of bilateral posterior subcapsular cataracts (PSCs) in a 24‐
year‐old man with an allergic conjunctivitis history caused by a long‐term therapy with …

Differentiation-Dependent Effects of a New Recombinant Manganese Superoxide Dismutase on Human SK-N-BE Neuron-Like Cells

A Crestini, R Vona, M Lo Giudice, M Sbriccoli… - Neurochemical …, 2019 - Springer
We have recently isolated a new isoform of recombinant manganese superoxide dismutase
(rMnSOD) which provides a potent antitumor activity and strongly counteracts the …