Twenty-five years ago, the first mammalian Transient Receptor Potential Canonical (TRPC)
channel was cloned, opening the vast horizon of the TRPC field. Today, we know that there …

This review addresses classical questions concerning microvascular permeabiltiy in the light
of recent experimental work on intact microvascular beds, single perfused microvessels, and …

TRP channel proteins constitute a large and diverse family of proteins that are expressed in
many tissues and cell types. This family was designated TRP because of a spontaneously …

The Drosophila transient receptor potential protein (TRP) and its mammalian homologues
are thought to be Ca2+-permeable cation channels activated by G protein (Gq/11)–coupled …

Characterization of mammalian homologues ofDrosophila transient receptor potential
protein (TRP) is an important clue to understand molecular mechanisms underlying Ca 2+ …

A steadily increasing number of cDNAs for proteins that are structurally related to the TRP
ion channels have been cloned in recent years. All these proteins display a topology of six …

Phototransduction in invertebrate microvillar photoreceptors is thought to be mediated by the
activation of phospholipase C (PLC), but how this leads to gating of the light-sensitive …

Hormonal stimulation of G q-protein coupled receptors triggers Ca 2+ mobilization from
internal stores. This is followed by a Ca 2+ entry through the plasma membrane. Drosophila …

Homologues of Drosophilia transient receptor potential (TRP) have been proposed to be
unitary subunits of plasma membrane ion channels that are activated as a consequence of …

The function (s) of the genes (PKD1 and PKD 2) responsible for the majority of cases of
autosomal dominant polycystic kidney disease is unknown. While PKD1 encodes a large …