Cognitive and behavioural flexibility: neural mechanisms and clinical considerations

LQ Uddin - Nature Reviews Neuroscience, 2021 - nature.com
Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and
behaviours in response to changing environmental demands. Brain mechanisms enabling …

The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging

HA Deery, R Di Paolo, C Moran, GF Egan… - …, 2023 - Wiley Online Library
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

Task-switching performance improvements after Tai Chi Chuan training are associated with greater prefrontal activation in older adults

MT Wu, PF Tang, JOS Goh, TL Chou… - Frontiers in aging …, 2018 - frontiersin.org
Studies have shown that Tai Chi Chuan (TCC) training has benefits on task-switching ability.
However, the neural correlates underlying the effects of TCC training on task-switching …

Dissociable neural mechanisms of cognition and well-being in youth versus healthy aging.

G Grennan, PP Balasubramani, N Vahidi… - Psychology and …, 2022 - psycnet.apa.org
Mental health, cognition, and their underlying neural processes in healthy aging are rarely
studied simultaneously. Here, in a sample of healthy younger (n= 62) and older (n= 54) …

Acute stress impacts reaction times in older but not in young adults in a flanker task

G Mikneviciute, J Allaert, MM Pulopulos, R De Raedt… - Scientific Reports, 2023 - nature.com
Acute psychosocial stress effects on inhibition have been investigated in young adults, but
little is known about these effects in older adults. The present study investigated effects of …

[HTML][HTML] Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease

CA Brown, NF Johnson, AJ Anderson-Mooney… - NeuroImage: Clinical, 2017 - Elsevier
We developed a merged younger-older adult template of the fornix and demonstrated its
utility for studies of aging and preclinical Alzheimer's disease (AD). In Experiment 1 …

Aging with HIV-1 infection: motor functions, cognition, and attention–a comparison with Parkinson's disease

S DeVaughn, EM Müller-Oehring, B Markey… - Neuropsychology …, 2015 - Springer
Recent advances in highly active anti-retroviral therapy (HAART) in their various
combinations have dramatically increased the life expectancies of HIV-infected persons …

Association between intensity or accumulating pattern of physical activity and executive function in community-dwelling older adults: A cross-sectional study with …

K Hyodo, N Kitano, A Ueno, D Yamaguchi… - Frontiers in Human …, 2023 - frontiersin.org
Objective Previous studies have suggested a positive association between physical activity
(PA) and executive function in older adults. However, they did not adequately consider the …

Age differences in the subcomponents of executive functioning

T Maldonado, JM Orr, JRM Goen… - The Journals of …, 2020 - academic.oup.com
Objectives Across the life span, deficits in executive functioning (EF) are associated with
poor behavioral control and failure to achieve goals. Though EF is often discussed as one …

Longitudinal alterations to brain function, structure, and cognitive performance in healthy older adults: A fMRI-DTI study

JG Hakun, Z Zhu, CA Brown, NF Johnson, BT Gold - Neuropsychologia, 2015 - Elsevier
Cross-sectional research has shown that older adults tend to have different frontal cortex
activation patterns, poorer brain structure, and lower task performance than younger adults …