There has been an upsurge of interest in the adipocyte coincident with the onset of the
obesity epidemic and the realization that adipose tissue plays a major role in the regulation …

Reproduction is a fundamental process for the preservation of the human species. This
process requires a sequence of orchestrated events that are necessary for a successful …

Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a
fundamental role in the regulation of bone organogenesis through the activation of receptor …

MicroRNAs (miRNAs) are small noncoding RNAs that regulate gene expression and,
therefore, biological processes in different tissues. A major function of miRNAs in adipose …

Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into several
tissues, such as bone, cartilage, and fat. Glucocorticoids affect a variety of biological …

Lineage progression in osteoblasts and chondrocytes is stringently controlled by the cell-
fate–determining transcription factor Runx2. In this study, we directly addressed whether …

The formation of adipocytes from precursor stem cells involves a complex and highly
orchestrated programme of gene expression. Our understanding of the basic network of …

MicroRNAs (miRNAs) repress cellular protein levels to provide a sophisticated parameter of
gene regulation that coordinates a broad spectrum of biological processes. Bone …

Cartilage and bone are severely affected by glucocorticoids (GCs), steroid hormones that
are frequently used to treat inflammatory diseases. Major complications associated with long …

MicroRNAs (miRNAs) interfere with translation of specific target mRNAs and are thought to
thereby regulate many cellular processes. Recent studies have suggested that miRNAs …