The road to low-dose aspirin therapy for the prevention of preeclampsia began in the 1980s
with the discovery that there was increased thromboxane and decreased prostacyclin …

Pregnancy is associated with a significant procoagulant shift in the hemostatic system
balance as well as other metabolic changes. Pregnancy can thereby provoke manifestation …

Objective: An imbalance between maternal angiogenic/anti-angiogenic factors
concentrations has been observed in preeclampsia (PE) and other obstetrical syndromes …

Aims: To characterize the transcriptome of human myometrium during spontaneous labor at
term. Methods: Myometrium was obtained from women with (n= 19) and without labor (n …

Objective: To prospectively determine the prognostic value of maternal plasma
concentrations of placental growth factor (PlGF), soluble endoglin (sEng) and soluble …

Background Pre-eclampsia is a complication of pregnancy associated with activation of
coagulation. It is caused by the placenta, which sheds increased amounts of …

Objective: The objective of this study was to determine the profiles of maternal plasma
soluble adhesion molecules in patients with preeclampsia, small-for-gestational-age (SGA) …

Pre-eclampsia (PE) complicates around 3% of all pregnancies and is one of the most
common causes of maternal mortality worldwide. The pathophysiology of PE remains …

Objective: Endocan, a dermatan sulphate proteoglycan produced by endothelial cells, is
considered a biomarker for endothelial cell activation/dysfunction. Preeclampsia is …

Objective: Obesity, insulin resistance, and dyslipidemia are associated with preeclampsia.
Recently,“adipose tissue failure”, characterized by dysregulation of adipokine production …