Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

The incidence of autoimmune diseases is increasing. Antinuclear antibody (ANA) testing is a
critical tool for their diagnosis. However, ANA prevalence in healthy persons has increased …

Systemic sclerosis (SSc) is an autoimmune connective tissue disorder, characterized by
multisystem involvement, vasculopathy, and fibrosis. An increased risk of malignancy is …

Background Endometriosis is recognized as an estrogen-dependent inflammation disorder,
estimated to affect 8%-15% of women of childbearing age. Currently, the etiology and …

Background Citrulline post-translational modification of proteins is mediated by protein
arginine deiminase (PADI) family members and has been associated with autoimmune …

Abstract Purpose Immune checkpoint inhibitors (ICIs) show promising clinical activity in
advanced cancers. However, the safety and efficacy of PD-1/PD-L1 blockade in patients with …

Simple Summary Cancer is one of the main causes of death worldwide and early detection
is crucial for effective treatment. Scientists have therefore focused on the identification of …

Background The presence of autoantibodies in the serum of cancer patients has been
associated with immune‐checkpoint inhibitor (ICI) therapy response and immune‐related …

Background Antinuclear antibodies (ANA) are antibodies present in several autoimmune
disorders. However, a large proportion of the general population (20%) also have a positive …

Immune-related adverse events (irAEs) are unpredictable autoimmune-like toxicities
induced by immune checkpoint inhibitors (ICI). irAEs are a consequence of a breakdown in …