Although the nuclear pore complex (NPC) is best known for its primary function as the key
regulator of molecular traffic between the cytoplasm and the nucleus, a growing body of …

Nuclear pore complexes (NPCs) are multiprotein aqueous channels that penetrate the
nuclear envelope connecting the nucleus and the cytoplasm. NPCs consist of multiple …

Recently, many of the enzymes responsible for the addition and removal of ubiquitin from
the histones H2A and H2B have been identified and characterized. From these studies, it …

Nuclear pore complexes (NPCs) are vital to nuclear–cytoplasmic communication in
eukaryotes. The yeast NPC‐associated TREX‐2 complex, also known as the Thp1–Sac3 …

Nuclear pore complexes are large aqueous channels that penetrate the nuclear envelope,
thereby connecting the nuclear interior with the cytoplasm. Until recently, these …

Transcriptional activators, several different coactivators, and general transcription factors are
necessary to access specific loci in the dense chromatin structure to allow precise initiation …

The SAGA complex provides a paradigm for multisubunit histone modifying complexes.
Although first characterized as a histone acetyltransferase, because of the Gcn5 subunit …

The combinatorial action of transcription factors drives cell-type-specific gene expression
patterns. However, transcription factor binding and gene regulation occur in the context of …

Genome-wide siRNA screens have identified host cell factors important for efficient HIV
infection, among which are nuclear pore proteins such as RanBP2/Nup358 and the …

The interaction of nuclear pore proteins (Nups) with active genes can promote their
transcription. In yeast, some inducible genes interact with the nuclear pore complex both …