The RAF/MEK/ERK signaling pathway regulates diverse cellular processes as exemplified
by cell proliferation, differentiation, motility, and survival. Activation of ERK1/2 generally …

The industrial wastes, sewage effluents, agricultural run-off and decomposition of biological
waste may cause high environmental concentration of chemicals that can interfere with the …

Long-term ingestion of arsenicals, a heterogeneous group of toxic compounds, has been
associated with a wide spectrum of human pathologies, which include various malignancies …

Arsenic, a naturally ubiquitous element, is found in foods and environment. Cardiac
dysfunction is one of the major causes of morbidity and mortality in the world. Arsenic …

Sesamin, a major lignan derived from sesame seeds, has been reported to have many
benefits and medicinal properties. However, its protective effects against fluoride-induced …

Arsenic (As) in the aquatic environment is a considerable environmental issue, previous
studies have reported the toxic effects of low concentrations (≤ 150 μg/L) of As on fish …

Nickel (Ni) is ubiquitous in the biosphere and is a common component of natural fresh
waters. When present in high concentrations, it becomes toxic to aquatic organisms. It is …

Arsenite is an important carcinogen and toxic compound, causing various deleterious effects
through multiple mechanisms. In this review, we focused on mitochondrial ROS (mitoROS) …

The present study evaluated the effects of exposure (28 days) to a sub-lethal concentration
of cadmium (Cd)(0.65 mg CdCl 2 L− 1) on the immune responses and expression of …

Background Metal exposure were assumed to be closely related with declined renal
function, but the conclusions were controversial. We employed diverse statistical models …