Multiple molecular recognition and catalysis. A multifunctional anion receptor bearing an anion binding site, an intercalating group, and a catalytic site for nucleotide …

MW Hosseini, AJ Blacker, JM Lehn - Journal of the American …, 1990 - ACS Publications
The multifunctional receptor molecule 2 has been designedand synthesized in order to
achieve higher molecular recognition and reaction selectivity via multiple interactions with …

Rigid molecular tweezers: synthesis, characterization, and complexation chemistry of a diacridine

SC Zimmerman, CM VanZyl - Journal of the American Chemical …, 1987 - ACS Publications
4a in a 54% yield. 12 Condensation of 4a with benzaldehyde (4% KOH in MeOH) formed
benzylidene 5a (49% yield). Coupling of 5a with 4a inperchloric acid, as described by …

Structural perturbations in DNA caused by bis-intercalation of ditercalinium visualised by atomic force microscopy

T Berge, NS Jenkins, RB Hopkirk… - Nucleic acids …, 2002 - academic.oup.com
Atomic force microscopy (AFM) has been used to examine perturbations in the tertiary
structure of DNA induced by the binding of ditercalinium, a DNA bis‐intercalator with strong …

An efficient and facile one-step synthesis of highly substituted thiophenes

FM Moghaddam, HZ Boinee - Tetrahedron, 2004 - Elsevier
An efficient and facile one-step synthesis of highly substituted thiophenes - ScienceDirect Skip
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Interactions of acyclic and cyclic bis-phenanthridinium derivatives with ss-and ds-polynucleotides

I Piantanida, BS Palm, P Čudić, M Žinić, HJ Schneider - Tetrahedron, 2004 - Elsevier
The acyclic bis-phenanthridinium ligands, and the cyclic analogue bind to ss-RNA by bis-
intercalation. Due to it's shorter linker exhibits mono-intercalative binding to ds …

Synthesis of Two Acridine Conjugates of the Bis (phenanthroline) Ligand “Clip‐Phen” and Evaluation of the Nuclease Activity of the Corresponding Copper …

SA Ross, M Pitié, B Meunier - European journal of inorganic …, 1999 - Wiley Online Library
The synthesis of three novel derivatives [N‐acetyl‐Clip‐Phen (1), Clip‐Phen‐
hexylaminoacridine (4) and Clip‐Phen‐hexylchloromethoxyaminoacridine (5)] of the bis …

Novel bifunctional Acridine− Acridinium conjugates: Synthesis and study of their chromophore-selective electron-transfer and DNA-binding properties

E Kuruvilla, J Joseph, D Ramaiah - The Journal of Physical …, 2005 - ACS Publications
Novel bifunctional conjugates 1− 3, with varying polymethylene spacer groups, were
synthesized, and their DNA interactions have been investigated by various biophysical …

Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, imunium ions, and peroxides

JR Ames, MD Ryan, DL Klyman, P Kovacic - … of Free Radicals in Biology & …, 1985 - Elsevier
A mechanism of action is proposed that encompasses almost all of the main categories of
antimalarial agents: quinones and precursors, dapsone metabolites, metal complexes of …

Structural characterisation of bisintercalation in higher-order DNA at a junction-like quadruplex

SCM Teixeira, JH Thorpe, AK Todd, HR Powell… - Journal of molecular …, 2002 - Elsevier
We report the single-crystal X-ray structure for the complex of the bisacridine bis-(9-
aminooctyl (2-(dimethylaminoethyl) acridine-4-carboxamide)) with the oligonucleotide d …

Interaction of a macrocyclic bisacridine with DNA

JM Veal, Y Li, SC Zimmerman, CR Lamberson… - Biochemistry, 1990 - ACS Publications
Materials and Methods Visible Spectroscopy. Visible spectroscopy was performed by using
a Cary 2200 spectrophotometer. MES buffer (10 mM MES, 1 mM EDTA, pH 6.5) containing …