Coronavirus accessory protein ORF3 biology and its contribution to viral behavior and pathogenesis

F Si, S Song, R Yu, Z Li, W Wei, C Wu - Iscience, 2023 - cell.com
Coronavirus porcine epidemic diarrhea virus (PEDV) is classified in the genus
Alphacoronavirus, family Coronaviridae that encodes the only accessory protein, ORF3 …

Elucidating the Implications of Norovirus N- and O-Glycosylation, O-GlcNAcylation, and Phosphorylation

CC Cheng, GM Ke, PY Chu, LY Ke - Viruses, 2023 - mdpi.com
Norovirus is the most common cause of foodborne gastroenteritis, affecting millions of
people worldwide annually. Among the ten genotypes (GI–GX) of norovirus, only GI, GII, GIV …

Generation of single-round infectious rotavirus with a mutation in the intermediate capsid protein VP6

T Kotaki, Y Kanai, M Onishi, S Minami, Z Chen… - Journal of …, 2024 - Am Soc Microbiol
Rotavirus causes severe diarrhea in infants. Although live attenuated rotavirus vaccines are
available, vaccine-derived infections have been reported, which warrants development of …

N-glycosylation of the envelope glycoprotein I is essential for the proliferation and virulence of the duck plague virus

Y Ning, M Wang, A Cheng, Q Yang, B Tian, X Ou… - Veterinary …, 2024 - Springer
Duck plague virus (DPV) causes the highly pathogenic duck plague, and the envelope
glycoprotein I (gI), as one of the key virulence genes, has not yet had its critical virulence …

[HTML][HTML] Rotaviruses and Rotavirus Vaccines: Special Issue Editorial

JT Patton, U Desselberger - Viruses, 2024 - mdpi.com
Species A rotaviruses (RVA) are a major cause of acute gastroenteritis in infants and young
children and in the young of various mammalian and avian species [1–3]. Since 2006 …

Proprotein convertase cleavage of Ictalurid herpesvirus 1 spike-like protein ORF46 is modulated by N-glycosylation

F Yu, J Xu, H Chen, S Song, C Nie, K Hao, Z Zhao - Virology, 2024 - Elsevier
Viral spike proteins undergo a special maturation process that enables host cell receptor
recognition, membrane fusion, and viral entry, facilitating effective virus infection. Here, we …

The synergy of recombinant NSP4 and VP4 from porcine rotavirus elicited a strong mucosal response

S Li, X Tang, J Zhou, X Bian, J Wang, L Gu, X Zhu… - Virology, 2024 - Elsevier
Porcine rotavirus (PoRV) is one of the main pathogens causing diarrhea in piglets, and
multiple genotypes coexist. However, an effective vaccine is currently lacking. Here, the …

A suitable and efficient optimization system for the culture of Chlamydia trachomatis in adult inclusion conjunctivitis

Y Wei, X Xu, L Wang, Q Chen, J Li, X Liu… - Pathogens and …, 2024 - academic.oup.com
The prevalence of Chlamydia trachomatis infection in the genitourinary tract is increasing,
with an annual rise of 9 million cases. Individuals afflicted with these infections are at a …

[HTML][HTML] 轮状病毒感染机制研究进展

韩郝涛, 杨学磊 - Advances in Clinical Medicine, 2024 - hanspub.org
轮状病毒是世界范围内引起儿童腹泻死亡的最重要的病原体之一. 其感染机制一直是研究热点,
近年来在分子水平及免疫学等方面已取得了显著进展. 本文对轮状病毒的一般生物学特征进行了 …

Viroporin activity from rotavirus nonstructural protein 4 induces intercellular calcium waves that contribute to pathogenesis

JT Gebert, FJ Scribano, KA Engevik, AA Philip… - bioRxiv, 2024 - biorxiv.org
Acute gastroenteritis remains the second leading cause of death among children under the
age of 5 worldwide. While enteric viruses are the most common etiology, the drivers of their …