Low temperature photothermal therapy: Advances and perspectives

K Yang, S Zhao, B Li, B Wang, M Lan, X Song - Coordination Chemistry …, 2022 - Elsevier
Photothermal therapy (PTT) has received increasing attention due to its high selectivity, non-
invasiveness, negligible drug resistance, oxygen independence, and minimal side effects. In …

Breast cancer stem cells: a novel therapeutic target

S Gangopadhyay, A Nandy, P Hor… - Clinical breast cancer, 2013 - Elsevier
Breast cancer stem cells (BCSCs), characterized by the CD44+/CD24−/low marker, are
attributed with features that are demonstrated by the disease itself, such as growth of tumor …

Heat shock protein 90: inhibitors in clinical trials

MA Biamonte, R Van de Water, JW Arndt… - Journal of medicinal …, 2010 - ACS Publications
The function of the heat shock proteins (HSPsa) is to fold and maintain the proper
conformation of other proteins, referred to as “clients”. HSPs are therefore molecular …

Anticancer gold (III) porphyrins target mitochondrial chaperone Hsp60

D Hu, Y Liu, YT Lai, KC Tong, YM Fung… - Angewandte Chemie …, 2016 - Wiley Online Library
Identification of the molecular target (s) of anticancer metal complexes is a formidable
challenge since most of them are unstable toward ligand exchange reaction (s) or biological …

Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB

L Wei, TT Liu, HH Wang, HM Hong, AL Yu… - Breast cancer …, 2011 - Springer
Abstract Introduction Heat shock proteins (HSPs) are normally induced under environmental
stress to serve as chaperones for maintenance of correct protein folding but they are often …

Heat shock proteins create a signature to predict the clinical outcome in breast cancer

M Klimczak, P Biecek, A Zylicz, M Zylicz - Scientific reports, 2019 - nature.com
Abstract Utilizing The Cancer Genome Atlas (TCGA) and KM plotter databases we identified
six heat shock proteins associated with survival of breast cancer patients. The survival …

Candida albicans Heat Shock Proteins and Hsps-Associated Signaling Pathways as Potential Antifungal Targets

Y Gong, T Li, C Yu, S Sun - Frontiers in cellular and infection …, 2017 - frontiersin.org
In recent decades, the incidence of invasive fungal infections has increased notably.
Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on …

Heat shock factor 1 promotes invasion and metastasis of hepatocellular carcinoma in vitro and in vivo

F Fang, R Chang, L Yang - Cancer, 2012 - Wiley Online Library
BACKGROUND: Heat shock factor 1 (HSF1) is a powerful, multifaceted modifier of
carcinogenesis. However, the clinical significance and biologic function of HSF1 in …

Quercetin suppresses drug-resistant spheres via the p38 MAPK–Hsp27 apoptotic pathway in oral cancer cells

SF Chen, S Nieh, SW Jao, CL Liu, CH Wu, YC Chang… - PloS one, 2012 - journals.plos.org
Background Treatment failure in oral squamous cell carcinoma (OSCC) leading to local
recurrence (s) and metastases is mainly due to drug resistance. Cancer stem cells (CSCs) …

[HTML][HTML] Targeting the heat shock response induced by modulated electro-hyperthermia (mEHT) in cancer

P Viana, P Hamar - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2024 - Elsevier
Abstract The Heat Shock Response (HSR) is a cellular stress reaction crucial for cell survival
against stressors, including heat, in both healthy and cancer cells. Modulated electro …