Tenascin-C is an extracellular matrix glycoprotein that is specifically and transiently
expressed upon tissue injury. Upon tissue damage, tenascin-C plays a multitude of different …

Atherosclerotic cardiovascular disease (CVD) is a major health problem in the United States
and around the world. Evidence accumulated over decades convincingly demonstrates that …

Objective—Comparison of gene expression in stable versus unstable atherosclerotic plaque
may be confounded by interpatient variability. The aim of this study was to identify …

Calcification is independently associated with cardiovascular events and morbidity. The
calcification burden in atherosclerotic lesions quantitatively and qualitatively differs between …

Background—The molecular pathophysiology of coronary artery disease (CAD) includes
cytokine release and a localized inflammatory response within the vessel wall. The extent to …

Systemic and local inflammation plays a prominent role in the pathogenesis of
atherosclerotic coronary artery disease, but the relationship of whole blood gene expression …

The concept of sparsity is more and more central to practical data analysis and inference
with increasingly high-dimensional data. Gene expression genomics is a key example …

Background—Although many genetic epidemiology and biomarker studies have been
conducted to examine associations of genetic variants and circulating proteins with …

Numerous recent studies have demonstrated the use of genomic data, particularly gene
expression signatures, as clinical prognostic factors in cancer and other complex diseases …

The development of microarray technology has revolutionized RNA and deoxyribonucleic
acid (DNA) research. In contrast with traditional biological assays, microarrays allow the …