Experimental autoimmune encephalomyelitis (EAE) is the most commonly used experimental model for the human inflammatory demyelinating disease, multiple sclerosis …
C Larochelle, JI Alvarez, A Prat - FEBS letters, 2011 - Elsevier
The presence of the blood–brain barrier (BBB) restricts the movement of soluble mediators and leukocytes from the periphery to the central nervous system (CNS). Leukocyte entry into …
The treatment of various central nervous system (CNS) diseases has been challenging, despite the rapid development of several novel treatment approaches. The blood–brain …
Multiple sclerosis (MS) is an autoimmune disease characterized by recurrent episodes of demyelination and axonal lesion mediated by CD4+ T cells with a proinflammatory Th1 and …
Neuroinflammation is involved in several neurodegenerative disorders and emerging evidence indicates that it constitutes a critical process that is required for the progression of …
R Bagheri, M Ghaedi, A Asfaram, EA Dil, H Javadian - Polyhedron, 2019 - Elsevier
In the present work, the activated carbon (AC) adsorbent with multimodal pore size distribution prepared from Amygdalus scoparia as low-cost and locally available source was …
M De Bock, N Wang, E Decrock, M Bol… - Progress in …, 2013 - Elsevier
Situated between the circulation and the brain, the blood–brain barrier (BBB) protects the brain from circulating toxins while securing a specialized environment for neuro-glial …
R Pacheco, F Contreras, M Zouali - Frontiers in immunology, 2014 - frontiersin.org
Bidirectional interactions between the immune and the nervous systems are of considerable interest both for deciphering their functioning and for designing novel therapeutic strategies …
Neurotransmitters are endogenous chemicals that allow neurons to communicate with each other throughout the body. They enable the brain to provide a variety of functions, through …