In women, endometrial morphology and function undergo characteristic changes every
menstrual cycle. These changes are crucial for perpetuation of the species and are …

In mammalian tissues, at least two isozymes of 11β-hydroxysteroid dehydrogenase (11β-
HSD) catalyze the interconversion of hormonally active C11-hydroxylated corticosteroids …

The endometrium contains a unique subset of uterine-specific natural killer (uNK) cells, the
proposed functions of which include a role in decidualization, menstruation, and …

In the past few decades, new and more efficient techniques to help solve fertility problems
have become widely available throughout the developed world. These techniques include …

BACKGROUND Despite extensive studies of the developmental consequences of increased
glucocorticoid exposure in mid-to late pregnancy, relatively little is known regarding the …

Elevated insulin-like growth factor binding protein (IGFBP) levels, including IGFBP-1, occur
in renal failure, and may contribute towards reduced IGF bioactivity in uraemia. The reduced …

The human endometrium is a unique tissue that has to undergo cycles of proliferation,
differentiation, destruction and repair. This ensures that the endometrium is optimally …

Context Endometrial insulin resistance (IR) may account for the endometrial dysfunction in
polycystic ovary syndrome (PCOS). The underlying mechanism remains to be elucidated …

The 11β-hydroxysteroid dehydrogenase enzymes (11β-HSD) interconvert cortisol and
cortisone in man, and corticosterone and 11-dehydrocorticosterone in rodents. Two distantly …

Key reproductive events, such as menstruation and implantation, are considered to be
inflammatory processes and glucocorticoids act as anti-inflammatory agents. The balance of …