Cognitive-behavioral therapies (CBTs) are the most widely studied form of psychotherapy for
disorders like depression and anxiety. Nonetheless, there is heterogeneity in response to …

Background The Common Elements Toolbox (COMET) is an unguided digital single-session
intervention (SSI) based on principles of cognitive behavioral therapy and positive …

Written by two leading experts in the field, this welcome third edition of Children in Difficulty:
A guide to understanding and helping discusses some of the most common, yet …

Objectives Specifiers for a major depressive disorder (MDE) are supposed to reduce
diagnostic heterogeneity. However, recent literature challenges the idea that the atypical …

The placebo response is a highly complex psychosocial-biological phenomenon that has
challenged drug development for decades, particularly in neurological and psychiatric …

Efforts to develop an individualized treatment rule (ITR) to optimize major depressive
disorder (MDD) treatment with antidepressant medication (ADM), psychotherapy, or …

Studies suggest that depression severity and duration interact to predict outcomes in
depression treatment. To our knowledge, no study has explored this question in a sample …

Abstract Introduction Doing What Matters in Times of Stress (DWM) is a five-module
transdiagnostic guided self-help (GSH) intervention developed by the World Health …

Objective This evidence-based update (EBU) builds on three previous reviews (1998, 2008,
2017) sponsored by the Society of Clinical Child and Adolescent Psychology with the aim of …

Background Although research shows that more depressed patients respond to combined
antidepressants (ADM) and psychotherapy than either alone, many patients do not respond …