During retinal neurogenesis, diverse cellular subtypes originate from multipotent neural
progenitors in a spatiotemporal order leading to a highly specialized laminar structure …

Introduction Epithelial-mesenchymal transition (EMT) of retinal pigment epithelial (RPE)
cells is related to the pathogenesis of various retinopathies including age-related macular …

Rhegmatogenous retinal detachment (RRD) is an ophthalmic emergency, which usually
requires prompt surgery to prevent further detachment and restore sensory function …

Neurodegenerative diseases remain incompletely understood and therapies are needed.
Stem cell-derived organoid models facilitate fundamental and translational medicine …

Cannabinoids have been suggested to protect retinal ganglion cells in different models of
toxicity, but their effects on other retinal neurons are poorly known. We investigated the …

Purpose: Toll‐like receptor 3 (TLR3) is a receptor of the innate immune system, recognizing
double‐stranded RNA. TLR3 can lead to cytokine release or apoptosis and has recently …

Glaucoma is a common cause of visual impairment and blindness, characterized by retinal
ganglion cell (RGC) death. The mechanisms that trigger the development of glaucoma …

The mitogen-activated protein kinase (MAPK) pathway has been shown to be involved in
both neurodevelopment and neurodegeneration. c-Jun N-terminal kinase (JNK), a MAPK …

Purpose.: Gliosis is the response of glial cells within retinal tissue to injury. It can be
beneficial in the short term, but if the response is extended it can lead to scar formation …

X‐linked juvenile retinoschisis (XLRS) is a hereditary retinal dystrophy in young males,
caused by mutations in the RS 1 gene. The function of the encoded protein, termed …