Isochores and the evolutionary genomics of vertebrates

G Bernardi - Gene, 2000 - Elsevier
The nuclear genomes of vertebrates are mosaics of isochores, very long stretches (≫
300kb) of DNA that are homogeneous in base composition and are compositionally …

The evolution of isochores

A Eyre-Walker, LD Hurst - Nature Reviews Genetics, 2001 - nature.com
One of the most striking features of mammalian chromosomes is the variation in G+ C
content that occurs over scales of hundreds of kilobases to megabases, the so …

A simple model based on mutation and selection explains trends in codon and amino-acid usage and GC composition within and across genomes

RD Knight, SJ Freeland, LF Landweber - Genome biology, 2001 - Springer
Background Correlations between genome composition (in terms of GC content) and usage
of particular codons and amino acids have been widely reported, but poorly explained. We …

Codon usage between genomes is constrained by genome-wide mutational processes

SL Chen, W Lee, AK Hottes… - Proceedings of the …, 2004 - National Acad Sciences
Analysis of genome-wide codon bias shows that only two parameters effectively differentiate
the genome-wide codon bias of 100 eubacterial and archaeal organisms. The first …

Nucleotide bias causes a genomewide bias in the amino acid composition of proteins

GAC Singer, DA Hickey - Molecular biology and evolution, 2000 - academic.oup.com
We analyzed the nucleotide contents of several completely sequenced genomes, and we
show that nucleotide bias can have a dramatic effect on the amino acid composition of the …

DNA G+ C content of the third codon position and codon usage biases of human genes

N Sueoka, Y Kawanishi - Gene, 2000 - Elsevier
The human genome, as in other eukaryotes, has a wide heterogeneity in the DNA base
composition. The evolutionary basis for this heterogeneity has been unknown. A previous …

[图书][B] Structural and evolutionary genomics: natural selection in genome evolution

G Bernardi - 2005 - books.google.com
Structural genomics is the study of the DNA of living organisms. Evolutionary genomics is
the study of the history of the genome. These subjects are closely interlinked. They are …

Comparison of codon usage measures and their applicability in prediction of microbial gene expressivity

F Supek, K Vlahoviček - BMC bioinformatics, 2005 - Springer
Background There are a number of methods (also called: measures) currently in use that
quantify codon usage in genes. These measures are often influenced by other sequence …

Plant tolerance to drought stress with emphasis on wheat

S Adel, N Carels - Plants, 2023 - mdpi.com
Environmental stresses, such as drought, have negative effects on crop yield. Drought is a
stress whose impact tends to increase in some critical regions. However, the worldwide …

Aerobiosis increases the genomic guanine plus cytosine content (GC%) in prokaryotes

H Naya, H Romero, A Zavala, B Alvarez… - Journal of molecular …, 2002 - Springer
The huge variation in the genomic guanine plus cytosine content (GC%) among prokar-
yotes has been explained by two mutually exclusive hypotheses, namely, selectionist and …