One of the most striking features of mammalian chromosomes is the variation in G+ C content that occurs over scales of hundreds of kilobases to megabases, the so …
Background Correlations between genome composition (in terms of GC content) and usage of particular codons and amino acids have been widely reported, but poorly explained. We …
SL Chen, W Lee, AK Hottes… - Proceedings of the …, 2004 - National Acad Sciences
Analysis of genome-wide codon bias shows that only two parameters effectively differentiate the genome-wide codon bias of 100 eubacterial and archaeal organisms. The first …
GAC Singer, DA Hickey - Molecular biology and evolution, 2000 - academic.oup.com
We analyzed the nucleotide contents of several completely sequenced genomes, and we show that nucleotide bias can have a dramatic effect on the amino acid composition of the …
The human genome, as in other eukaryotes, has a wide heterogeneity in the DNA base composition. The evolutionary basis for this heterogeneity has been unknown. A previous …
Structural genomics is the study of the DNA of living organisms. Evolutionary genomics is the study of the history of the genome. These subjects are closely interlinked. They are …
Background There are a number of methods (also called: measures) currently in use that quantify codon usage in genes. These measures are often influenced by other sequence …
Environmental stresses, such as drought, have negative effects on crop yield. Drought is a stress whose impact tends to increase in some critical regions. However, the worldwide …
H Naya, H Romero, A Zavala, B Alvarez… - Journal of molecular …, 2002 - Springer
The huge variation in the genomic guanine plus cytosine content (GC%) among prokar- yotes has been explained by two mutually exclusive hypotheses, namely, selectionist and …