Overweight and adiposity are risk factors for several diseases, like type 2 diabetes and
cancer. White adipose tissue is a major source for adipokines, comprising a diverse group of …

Background There is currently an unmet clinical need to develop better pharmacological
treatments to improve glucose handling in Type II Diabetes patients with obesity. To this end …

Chemerin is an immunomodulating factor secreted predominantly by adipose tissue and
skin. Processed by a variety of proteases linked to inflammation, it activates the G‐protein …

Chemerin is a novel adipokine that plays a major role in adipogenesis and lipid metabolism.
It also induces inflammation and affects insulin signaling, steroidogenesis and …

Chemerin is a widely distributed multifunctional secreted protein implicated in immune cell
migration, adipogenesis, osteoblastogenesis, angiogenesis, myogenesis, and glucose …

Chemerin is the product of the RARRES2 gene which is secreted as a precursor of 143
amino acids. That precursor is inactive, but proteases from the coagulation and fibrinolytic …

Chemerin is a small chemotactic protein and a key player in initiating the early immune
response. As an adipokine, chemerin is also involved in energy homeostasis and the …

While genome‐wide association studies as well as candidate gene studies have revealed a
great deal of insight into the contribution of genetics to obesity development and …

When chemerin was discovered in 1997, it was relegated to being a protein associated with
the normal skin function contrasting the setting of psoriasis. However, with the discovery of …

The skin is the largest and the most exposed organ in the body and its defense is regulated
at several anatomical levels. Here, we explore how skin layers, including the epidermis …