The differentiation and maturation of mesenchymal stem cells (MSCs) to mesodermal and
other lineages are known to be controlled by various extrinsic and intrinsic signals. The …

As ovarian tumors progress, they undergo a process of dedifferentiation, allowing adaptive
changes in growth and morphology that promote metastasis and chemoresistance. Herein …

The scaffolds, which morphologically and physiologically mimic natural features of the bone,
are of high demand for regenerative medicine. To address this challenge, we have …

Background The two major obstacles in the successful transplantation of islets for diabetes
treatment are inadequate supply of insulin-producing tissue and immune rejection. Induction …

The lysine methyltransferase SETD6 modifies the histone variant H2AZ, a key component of
nuclear receptor-dependent transcription. Herein, we report the identification of several …

TATA‐binding protein associated factor 4 (TAF4) is a subunit of the Transcription Factor IID
(TFIID) complex, a central player in transcription initiation. Other members of this multimeric …

Alternative splicing is a crucial regulator in stem cell biology, intricately influencing the
functions of various biological macromolecules, particularly pre-mRNAs and the resultant …

Abstract Three-dimensional (3D) customized scaffolds capable to mimic a native
extracellular matrix open new frontiers in cells manipulation and advanced therapy. The …

Methods and Results The regulatory motifs of RUNX2 exon 5 were analyzed using the
online SpliceAid program. The alternative splicing of RUNX2 exon 5 in DPSCs during …

The intervertebral disc (IVD) degeneration is initiated by cartilage endplate (CEP)
degeneration and is characterised by reduced chondrification. Cartilage endplate-derived …