Pathogenesis and Clinical Relevance of Candida Biofilms in Vulvovaginal Candidiasis

C Rodríguez-Cerdeira, E Martínez-Herrera… - Frontiers in …, 2020 - frontiersin.org
The ability of Candida spp. to form biofilms is crucial for its pathogenicity, and thus, it should
be considered an important virulence factor in vulvovaginal candidiasis (VVC) and recurrent …

A comprehensive overview of the medicinal chemistry of antifungal drugs: perspectives and promise

KC Howard, EK Dennis, DS Watt… - Chemical Society …, 2020 - pubs.rsc.org
The emergence of new fungal pathogens makes the development of new antifungal drugs a
medical imperative that in recent years motivates the talents of numerous investigators …

pH-responsive cellulose-based dual drug-loaded hydrogel for wound dressing

X Fan, L Yang, T Wang, T Sun, S Lu - European Polymer Journal, 2019 - Elsevier
A pH-responsive hydrogel having a drug combined effect was prepared for wound dressing
by using dialdehyde carboxymethyl cellulose, tobramycin, β-cyclodextrin derivative and …

Novel Therapies for Biofilm-Based Candida spp. Infections

L Černáková, C Light, B Salehi… - … Infectious Diseases and …, 2019 - Springer
The presence of fungal infections continue to grow worldwide, mostly in immunosuppressed
patients, and in individuals with continued antimicrobial treatments. Candida spp. are the …

Distorted gold (I)–phosphine complexes as antifungal agents

EK Dennis, JH Kim, S Parkin, SG Awuah… - Journal of medicinal …, 2019 - ACS Publications
Fungi cause serious nosocomial infections including candidiasis and aspergillosis, some of
which display reduced susceptibility to current antifungals. Inorganic compounds have been …

Designing new hybrid antibiotics: proline-rich antimicrobial peptides conjugated to the aminoglycoside tobramycin

S Gambato, O Bellotto, M Mardirossian… - Bioconjugate …, 2023 - ACS Publications
Resistance to aminoglycoside antibiotics is a serious problem, typically arising from
inactivating enzymes, reduced uptake, or increased efflux in the important pathogens for …

Anti-Candida activity of existing antibiotics and their derivatives when used alone or in combination with antifungals

Y Liu, W Wang, H Yan, D Wang, M Zhang… - Future …, 2019 - Taylor & Francis
Fungal infections are a growing challenge in immunocompromised patients, especially
candidiasis. The prolonged use of traditional antifungals to treat Candida infection has …

[HTML][HTML] Synthesis and Antibacterial Activity of New 6 ″-Modified Tobramycin Derivatives

KS Shapovalova, GV Zatonsky, EA Razumova… - …, 2024 - pmc.ncbi.nlm.nih.gov
Objectives: Aminoglycosides are one of the first classes of natural antibiotics which have not
lost relevance due to their broad spectrum of action against Gram-positive, Gram-negative …

Homogeneous catalyst containing Pd in the reduction of aryl azides to primary amines

E Cantopcu, E Aydinli, H Goksu - Journal of Chemical Sciences, 2022 - Springer
Abstract Commercially available dichloro [2, 2′-bis (diphenylphosphino)-1, 1′-binaphthyl]
palladium (II)(BINAP. PdCl2) homogeneous catalyst was used for the reduction of aryl …

Interest of Homodialkyl Neamine Derivatives against Resistant P. aeruginosa, E. coli, and β-Lactamases-Producing Bacteria—Effect of Alkyl Chain Length on the …

J Swain, C Dezanet, H Chalhoub, M Auquière… - International Journal of …, 2021 - mdpi.com
Development of novel therapeutics to treat antibiotic-resistant infections, especially those
caused by ESKAPE pathogens, is urgent. One of the most critical pathogens is P …