Objetivo: Investigar os fatores de risco associados ao adoecimento por hanseníase em
contatos de casos da doença. Métodos: Realizou-se uma revisão sistemática e metanálise …

Leprosy is a chronic infectious disease caused by an obligate intracellular bacterium known
as Mycobacterium leprae. Exposure to the bacillus is necessary, but this alone does not …

Objective—Our aim was to identify the role of the homeostatic chemokines CCL19 and
CCL21 and their common receptor CCR7 in atherogenesis and to study the relationships …

Objective: To investigate the risk factors associated with leprosy in contacts of patients.
Method: We carried out a systematic review and meta-analysis by searching the databases …

Many genes including HLA, KIR, and MICA genes, as well as polymorphisms in cytokines
have been investigated for their role in infectious disease. HLA alleles may influence not …

Leprosy is a chronic infectious disease, caused by Mycobacterium leprae, which affects skin
and peripheral nerves. Polymorphisms in genes associated with autophagy, metabolism …

Background Interferon-γ (IFN-γ) plays an important role in the control of Leishmania
infection. Blockade of IFN-γ signaling in mice increases lesion size and parasite load. In …

The large yellow croaker Larimichthys crocea is an important mariculture fish species in
China, and the bacterium Vibrio harveyi (V. harveyi) and the ciliate protozoan Cryptocaryon …

Previous studies identified the variant IFNG+ 874A/T (rs2430561) in the first intron of the
gene in association with mycobacterial infection, especially tuberculosis and leprosy. The …

Polymorphisms present in the TNF promoter region has shown to influence the gene
transcription. Leprosy displays different clinical manifestations according to the immune …