Plant_SNP_TATA_Z-Tester: A Web service that unequivocally estimates the impact of proximal promoter mutations on plant gene expression

D Rasskazov, I Chadaeva, E Sharypova… - International Journal of …, 2022 - mdpi.com
Synthetic targeted optimization of plant promoters is becoming a part of progress in
mainstream postgenomic agriculture along with hybridization of cultivated plants with wild …

How to Use SNP_TATA_Comparator to Find a Significant Change in Gene Expression Caused by the Regulatory SNP of This Gene's Promoter via a Change in …

M Ponomarenko, D Rasskazov… - BioMed Research …, 2015 - Wiley Online Library
The use of biomedical SNP markers of diseases can improve effectiveness of treatment.
Genotyping of patients with subsequent searching for SNPs more frequent than in norm is …

Obesity-related known and candidate SNP markers can significantly change affinity of TATA-binding protein for human gene promoters

OV Arkova, MP Ponomarenko, DA Rasskazov… - BMC genomics, 2015 - Springer
Background Obesity affects quality of life and life expectancy and is associated with
cardiovascular disorders, cancer, diabetes, reproductive disorders in women, prostate …

Candidate SNP markers of familial and sporadic Alzheimer's diseases are predicted by a significant change in the affinity of TATA-binding protein for human gene …

P Ponomarenko, I Chadaeva, DA Rasskazov… - Frontiers in Aging …, 2017 - frontiersin.org
While year after year, conditions, quality, and duration of human lives have been improving
due to the progress in science, technology, education, and medicine, only eight diseases …

Candidate SNP markers of aggressiveness-related complications and comorbidities of genetic diseases are predicted by a significant change in the affinity of TATA …

IV Chadaeva, MP Ponomarenko, DA Rasskazov… - BMC genomics, 2016 - Springer
Background Aggressiveness in humans is a hereditary behavioral trait that mobilizes all
systems of the body—first of all, the nervous and endocrine systems, and then the …

Candidate SNP markers significantly altering the affinity of TATA-binding protein for the promoters of human hub genes for atherogenesis, atherosclerosis and …

A Bogomolov, S Filonov, I Chadaeva… - International Journal of …, 2023 - mdpi.com
Atherosclerosis is a systemic disease in which focal lesions in arteries promote the build-up
of lipoproteins and cholesterol they are transporting. The development of atheroma …

Candidate SNP markers of gender-biased autoimmune complications of monogenic diseases are predicted by a significant change in the affinity of TATA-binding …

MP Ponomarenko, O Arkova, D Rasskazov… - Frontiers in …, 2016 - frontiersin.org
Some variations of human genome [for example, single nucleotide polymorphisms (SNPs)]
are markers of hereditary diseases and drug responses. Analysis of them can help to …

Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters

IV Chadaeva, PM Ponomarenko, DA Rasskazov… - BMC genomics, 2018 - Springer
Background The progress of medicine, science, technology, education, and culture
improves, year by year, quality of life and life expectancy of the populace. The modern …

Candidate SNP Markers of Chronopathologies Are Predicted by a Significant Change in the Affinity of TATA‐Binding Protein for Human Gene Promoters

P Ponomarenko, D Rasskazov, V Suslov… - BioMed Research …, 2016 - Wiley Online Library
Variations in human genome (eg, single nucleotide polymorphisms, SNPs) may be
associated with hereditary diseases, their complications, comorbidities, and drug responses …

Natural Selection Equally Supports the Human Tendencies in Subordination and Domination: A Genome-Wide Study With in silico Confirmation and in vivo …

I Chadaeva, P Ponomarenko, D Rasskazov… - Frontiers in …, 2019 - frontiersin.org
We proposed the following heuristic decision-making rule:“IF {an excess of a protein relating
to the nervous system is an experimentally known physiological marker of low pain …