Antibiotic resistance is currently one of the most important public health problems. The
golden age of antibiotic discovery ended decades ago, and new approaches are urgently …

The development of resistance to β-lactam antibiotics has made Staphylococcus aureus a
clinical burden on a global scale. MRSA (methicillin-resistant S. aureus) is commonly known …

Central metabolic pathways control virulence and antibiotic resistance, and constitute
potential targets for antibacterial drugs. In Staphylococcus aureus the role of the pentose …

Protein posttranslational modifications (PTMs) play important roles in regulating numerous
biological functions of prokaryotic and eukaryotic organisms. Lysine succinylation (Ksucc) …

Bacteria develop tolerance after transient exposure to antibiotics, and tolerance is a
significant driver of resistance. The purpose of this study is to evaluate the mechanisms …

Lysine succinylation (Ksuc) is a novel protein post-translational modification (PTM) wherein
a succinyl group modifies a lysine residue. Ksuc leads to significant chemical and structural …

Hydroxylamine (NH 2 OH) is a potentially toxic pollutant when it is present in water, as it can
damage both bacteria and the human body. It is still difficult to eliminate the toxic NH 2 OH in …

ABSTRACT Dr Merve Suzan Zeden works in the field of molecular bacteriology and
antibiotic resistance. In this mSphere of Influence article, she reflects on how three papers …

Different international agencies recognize that antibiotic resistance is one of the most severe
human health problems that humankind is facing. Traditionally, the introduction of new …

The pandemic of antibiotic resistance, particularly Staphylococcus aureus-related
resistance, is increasing frighteningly. The recommendation of wrong antibiotic drugs for …