Mechanisms regulating GLUT4 glucose transporter expression and glucose transport in skeletal muscle

A Zorzano, M Palacin, A Guma - Acta Physiologica …, 2005 - Wiley Online Library
Skeletal muscle is a major glucose‐utilizing tissue in the absorptive state and the major
glucose transporter expressed in muscle in adulthood is GLUT4. GLUT4 expression is …

Neurobarrier coupling in the brain: a partner of neurovascular and neurometabolic coupling?

L Leybaert - Journal of Cerebral Blood Flow & Metabolism, 2005 - journals.sagepub.com
Neurovascular and neurometabolic coupling help the brain to maintain an appropriate
energy flow to the neural tissue under conditions of increased neuronal activity. Both …

Transforming growth factor β1 (TGF-β1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-α signaling

F Viñals, J Pouysségur - Molecular and cellular biology, 2001 - Taylor & Francis
Mouse capillary endothelial cells (1G11 cell line) embedded in type I collagen gels undergo
in vitro angiogenesis. Cells rapidly reorganize and form capillary-like structures when …

Peroxisome proliferator-activated receptor γ thiazolidinedione agonists increase glucose metabolism in astrocytes

CD Russo, V Gavrilyuk, G Weinberg, A Almeida… - Journal of Biological …, 2003 - ASBMB
Activation of peroxisome proliferator-activated receptors (PPARs) can regulate brain
physiology and provide protection in models of neurological disease; however, neither their …

Invited review: Regulation of skeletal muscle GLUT-4 expression by exercise

GL Dohm - Journal of applied physiology, 2002 - journals.physiology.org
The amount of GLUT-4 protein is a primary factor in determining the maximal rate of glucose
transport into skeletal muscle. Therefore, it is important that we understand how exercise …

A novel role of neuregulin in skeletal muscle: neuregulin stimulates glucose uptake, glucose transporter translocation, and transporter expression in muscle cells

E Suárez, D Bach, J Cadefau, M Palacı́n… - Journal of biological …, 2001 - ASBMB
Neuregulins regulate the expression of acetylcholine receptor genes and induce
development of the neuromuscular junction in muscle. In studying whether neuregulins …

[HTML][HTML] Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes

R Hernandez, T Teruel, M Lorenzo - FEBS letters, 2001 - Elsevier
Insulin acutely stimulated glucose uptake in rat primary brown adipocytes in a PI3-kinase-
dependent but p70S6-kinase-independent manner. Since Akt represents an intermediate …

Multiple signalling pathways involved in β2‐adrenoceptor‐mediated glucose uptake in rat skeletal muscle cells

J Nevzorova, BA Evans, T Bengtsson… - British journal of …, 2006 - Wiley Online Library
β‐adrenoceptor (AR) agonists increase 2‐deoxy‐[3H]‐d‐glucose uptake (GU) via β2‐AR in
rat L6 cells. The β‐AR agonists, zinterol (β2‐AR) and (−)‐isoprenaline, increased cAMP …

Influence of melatonin receptor signalling on parameters involved in blood glucose regulation

I Bazwinsky‐Wutschke, L Bieseke… - Journal of pineal …, 2014 - Wiley Online Library
The pineal hormone melatonin is known to influence insulin secretion via the G‐protein‐
coupled receptor isoforms MT 1 and MT 2. The present study was aimed to further elucide …

A novel functional co-operation between MyoD, MEF2 and TRα1 is sufficient for the induction of GLUT4 gene transcription

T Santalucı́a, H Moreno, M Palacı́n, MH Yacoub… - Journal of molecular …, 2001 - Elsevier
We report tripartite co-operation between MyoD, myocyte enhancer factor-2 (MEF2) and the
thyroid hormone receptor (TRα1) that takes place in the context of an 82-bp muscle-specific …