Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge

H Elkhenany, A El-Derby, M Abd Elkodous… - Stem Cell Research & …, 2022 - Springer
The amniotic membrane (Amnio-M) has various applications in regenerative medicine. It
acts as a highly biocompatible natural scaffold and as a source of several types of stem cells …

Cell therapy for wound healing

HJ You, SK Han - Journal of Korean medical science, 2014 - synapse.koreamed.org
In covering wounds, efforts should include utilization of the safest and least invasive
methods with goals of achieving optimal functional and cosmetic outcome. The recent …

Application of amniotic membrane in skin regeneration

N Fitriani, G Wilar, AC Narsa, AFA Mohammed… - Pharmaceutics, 2023 - mdpi.com
Amniotic membrane (AM) is an avascular structure composed of three different layers, which
contain collagen, extracellular matrix, and biologically active cells (stem cells). Collagen, a …

Immunomodulatory effects of amniotic membrane matrix incorporated into collagen scaffolds

RA Hortensius, JH Ebens… - Journal of Biomedical …, 2016 - Wiley Online Library
Adult tendon wound repair is characterized by the formation of disorganized collagen matrix
which leads to decreases in mechanical properties and scar formation. Studies have linked …

Incorporation of the amniotic membrane as an immunomodulatory design element in collagen scaffolds for tendon repair

RA Hortensius, JH Ebens, MJ Dewey… - … biomaterials science & …, 2018 - ACS Publications
Tendon injuries often require surgical intervention and even then result in poor outcomes
due to scar formation and repeated failure. Biomaterial implants offer the potential to …

In situ delivery of fibrin-based hydrogels prevents contraction and reduces inflammation

DM Burmeister, DC Roy, SC Becerra… - Journal of Burn Care …, 2017 - academic.oup.com
While early excision and grafting has revolutionized burn wound care, autologous split-
thickness skin grafts are sometimes unavailable. Tissue-engineered skin substitutes have …

Naturally derived biomaterials for addressing inflammation in tissue regeneration

RA Hortensius, BAC Harley - Experimental Biology and …, 2016 - journals.sagepub.com
Tissue regeneration strategies have traditionally relied on designing biomaterials that
closely mimic features of the native extracellular matrix (ECM) as a means to potentially …

Poly (lactide‐co‐ε‐caprolactone) scaffold promotes equivalent tissue integration and supports skin grafts compared to a predicate collagen scaffold

DS Ruppert, MM Mohammed… - Wound Repair and …, 2021 - Wiley Online Library
Dermal scarring from motor vehicle accidents, severe burns, military blasts, etc. is a major
problem affecting over 80 million people worldwide annually, many of whom suffer from …

Effects of polydeoxyribonucleotide in the treatment of pressure ulcers

JY Kim, CS Pak, JH Park, JH Jeong… - Journal of Korean …, 2014 - synapse.koreamed.org
This study aimed to examine the positive effects of polydeoxyribonucleotide (PDRN) on the
wound-healing process in pressure ulcers. In this randomized controlled trial, the effects of …

Three-dimensional decellularized amnion membrane scaffold as a novel tool for cancer research; cell behavior, drug resistance and cancer stem cell content

M Ganjibakhsh, F Mehraein, M Koruji… - Materials Science and …, 2019 - Elsevier
Background Cancer is the second leading cause of human death. Therefore,
comprehensive research and the appropriate tools are needed in this field. Animal models …