PET molecular imaging in drug development: the imaging and chemistry perspective
Positron emission tomography with selective radioligands advances the drug discovery and
development process by revealing information about target engagement, proof of …
development process by revealing information about target engagement, proof of …
PET radiotracers and fluorescent probes for imaging human carbonic anhydrase IX and XII in hypoxic tumors
Positron emission tomography (PET) and fluorescent imaging play a pivotal role in medical
diagnosis, biomedical oncologic research, and drug development process, which include …
diagnosis, biomedical oncologic research, and drug development process, which include …
A molecular toolbox of positron emission tomography tracers for general anesthesia mechanism research
X Wang, T Wang, X Fan, Z Zhang… - Journal of Medicinal …, 2023 - ACS Publications
With appropriate radiotracers, positron emission tomography (PET) allows direct or indirect
monitoring of the spatial and temporal distribution of anesthetics, neurotransmitters, and …
monitoring of the spatial and temporal distribution of anesthetics, neurotransmitters, and …
[HTML][HTML] India's Growing Nuclear Medicine Infrastructure and Emergence of Radiotheranotics in Cancer Care: Associated Challenges and the Opportunities to …
Background A historical pledge to use “atoms for peace” was taken after the landmark and
maiden speech of 34 th US president Dwight David Eisenhower in 1 st UN assembly meet in …
maiden speech of 34 th US president Dwight David Eisenhower in 1 st UN assembly meet in …
Synthetic methodologies and PET imaging applications of fluorine-18 radiotracers: a patent review
SG Nerella, A Bhattacharya, PS Thacker… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction Fluorine-18 is a promising radionuclide for developing novel PET radiotracers
due to its characteristic features such as convenient half-life, metabolic stability, good …
due to its characteristic features such as convenient half-life, metabolic stability, good …
Multi-patient dose synthesis of [18F]Flumazenil via a copper-mediated 18F-fluorination
Background Flumazenil (FMZ) is a functionally silent imidazobenzodiazepine which binds to
the benzodiazepine binding site of approximately 75% of the brain γ-aminobutyric acid-A …
the benzodiazepine binding site of approximately 75% of the brain γ-aminobutyric acid-A …
[HTML][HTML] Radiosynthesis of [18F]-flumazenil Using an Isotopic Approach
R Thakur, A Kumar, RK Joshi… - Indian Journal of Nuclear …, 2024 - journals.lww.com
Background: Fluorine-18 (18 F) flumazenil (FMZ) has been synthesized using various
precursors, and its role has been explored in imaging Gamma-aminobutyric acid-A …
precursors, and its role has been explored in imaging Gamma-aminobutyric acid-A …
Multi-patient dose synthesis of [18F] Flumazenil via a copper-mediated 18F-fluorination
G Thibault, D Gianluca, SN JW, JB Sap… - EJNMMI …, 2022 - search.proquest.com
Background Flumazenil (FMZ) is a functionally silent imidazobenzodiazepine which binds to
the benzodiazepine binding site of approximately 75% of the brain γ-aminobutyric acid-A …
the benzodiazepine binding site of approximately 75% of the brain γ-aminobutyric acid-A …