Radiation therapy is one of the most widely used therapies for malignancies. The
therapeutic use of heavy ions, such as carbon, has gained significant interest due to …

Charged particle therapy is generally regarded as cutting-edge technology in oncology.
Many proton therapy centres are active in the USA, Europe, and Asia, but only a few centres …

Cells manage to survive, thrive, and divide with high accuracy despite the constant threat of
DNA damage. Cells have evolved with several systems that efficiently repair spontaneous …

Compared to conventional photon-based external beam radiation (PhXRT), carbon ion
radiotherapy (CIRT) has superior dose distribution, higher linear energy transfer (LET), and …

The diagnosis of a glioblastoma is mainly made on the basis of their microscopic
appearance with the additional determination of epigenetic as well as mutational analyses …

Background Glioblastoma (GBM) is a highly malignant brain tumour that almost inevitably
progresses or recurs after first line standard of care. There is no consensus regarding the …

Based on its potent capacity to induce tumor cell death and to abrogate clonogenic survival,
radiotherapy is a key part of multimodal cancer treatment approaches. Numerous clinical …

Glioblastoma (GBM) is a highly invasive brain tumor, whose cells infiltrate surrounding
normal brain tissue beyond the lesion outlines visible in the current medical scans. These …

Abstract Purpose of Review Glioblastoma (GBM) is the most common malignant primary
brain tumor, and the available treatment options are limited. This article reviews the recent …

Abstract Background Both 18F-fluorodihydroxyphenylalanine (18F-DOPA) and 18F-
fluoroethyltyrosine (18F-FET) have already been used successfully for imaging of brain …