Gout, a disease recognized since antiquity, has increased in prevalence in recent years and
the clinical profile of this disease has become increasingly complex, owing to large numbers …

Gout is a common and very painful inflammatory arthritis caused by hyperuricaemia. This
Review provides an update on the genetics of hyperuricaemia and gout, including findings …

Background Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to
identify novel genes associated with serum uric acid concentration and gout. Methods …

Gout is the most common inflammatory joint disease in men, characterised by formation of
monosodium urate (MSU) crystals in the synovial fluid of joints and in other tissues. The …

Background: Although studies have shown that interleukin-1β (IL-1β) inhibitors can shorten
gout attacks, whether they can prevent gout attacks is unclear. Objective: To examine the …

Background Reduced kidney function is a risk factor for hyperuricaemia and gout, but limited
information on the burden of gout is available from studies of patients with chronic kidney …

Gout is a common disease which mostly occurs after middle age, but more people
nowadays develop it before the age of thirty. We investigated whether common dysfunction …

Background Gout is a chronic, inflammatory arthritis characterized by painful and debilitating
acute/episodic flares. Until recently, gout has been regarded as a minor medical problem, in …

Background: Gout is a painful and disabling inflammatory arthritis of increasing prevalence
associated with hyperuricemia and the deposition of monosodium urate crystals in soft …

Flavonoids are widely found in plants and many of them possess biological and
pharmacological activities. In the present study, we assessed the effects of the flavonoids …